α-亚麻酸乙酯制备和质量评价  

Preparation and Quality Evaluation of α-Ethyl Linolenate

作　　者：段建利[1] DUAN Jian-li(Provincial Demonstration Center of Experimental Pharmaceutical Teaching,School of Pharmaceutical Sciences,Wuhan University,Hubei Wuhan 430071,China)

机构地区：[1]武汉大学药学院、省级药学实验教学示范中心,湖北武汉430071

出　　处：《广州化工》2018年第22期105-107,共3页GuangZhou Chemical Industry

基　　金：武汉大学教学研究项目(2017JG056);武汉大学医学部教学研究项目(2018070)

摘　　要：以紫苏籽油为原料,利用碱催化条件下的酯交换反应,得到α-亚麻酸乙酯粗品,再用尿素包合法对α-亚麻酸乙酯粗品进行分离纯化,得到高纯度的α-亚麻酸乙酯,并对高纯度的α-亚麻酸乙酯建立初步质量评价体系。整个实验过程设计紧凑,安排合理,将理论知识灵活应用到实验课程中,涉及知识面广,实践性和应用性强,可作为综合性实验,大大提高学生对实验课程的兴趣。High purified α-ethyl linolenate was prepared through interesterification in basic condition by using perilla oil as material,and purified by urea adduction. The primary evaluation system of high purified α-ethyl linolenate was established,including the determination of acid value,iodine value,peroxide value,etc. The whole experimentation was well-designed,involved wide knowledge,applied theoretical knowledge to experimental courses flexibly,so it had the practical and applied nature. The experimentation can be used as a teaching case of integrative experiment,to enhance students＇ interest in experimental curriculum.

关 键 词：Α-亚麻酸乙酯 尿素包合 酯交换 

分 类 号：O6-33[理学—化学]