中西医结合治疗脾胃湿热型慢性胃炎伴Hp感染的疗效分析  

Curative effect analysis of traditional Chinese medicine and western medicine in the treatment of spleen and stomach damp heat type chronic gastritis combined with Hp infection

作　　者：洪顺忠[1] 王育斌[1] 林志金[1] 黄子成[1] 黄奕森[1] 陈相波[1] HONG Shunzhong;WANG Yubin;LIN Zhijin;HUANG Zicheng;HUANG Yisen;CHEN Xiangbo(Endoscopy Room,Quanzhou First Hospital Affiliated to Fujian Medical University,Quanzhou 362000,China)

机构地区：[1]福建医科大学附属泉州第一医院,福建泉州362000

出　　处：《中国现代医生》2018年第31期120-122,共3页China Modern Doctor

摘　　要：目的探讨中西医结合治疗脾胃湿热型慢性胃炎伴Hp感染的疗效分析。方法将2015年2月～2018年2月在我院消化内科治疗的256例脾胃湿热型慢性胃炎伴Hp感染患者根据随机数字表法分为两组,对照组单用西医方法治疗,观察组采用中西医结合治疗,比较两组患者的临床疗效、Hp根除率、症状改善情况、不良反应。结果观察组治疗有效率为96.88%,明显高于对照组的78.91%,差异有统计学意义(P<0.05);观察组Hp根除率为87.50%,明显高于对照组的71.09%,差异有统计学意义(P<0.05);观察组治疗后胃脘灼热、上腹胀痛、恶心呕吐、口苦口臭等中医证候积分明显低于对照组,差异有统计学意义(P<0.05);观察组胸闷、头晕、乏力、腹泻、皮疹等不良反应发生率明显低于对照组,差异有统计学意义(P<0.05)。结论中西医结合治疗脾胃湿热型慢性胃炎伴Hp感染的疗效显著,能提升Hp根除效果,促进症状缓解,且不良反应发生率低,具有积极的临床意义。Objective To investigate the efficacy of integrated traditional Chinese and Western medicine in the treatment of spleen and stomach damp heat type chronic gastritis combined with Hp infection. Methods A total of 256 patients with spleen-stomach damp-heat chronic gastritis combined with Hp infection who were treated in the department of gastroenterology in our hospital from February 2015 to February 2018 were divided into two groups according to the random number table. The control group was treated with western medicine alone. The observation group was treated with traditional Chinese and western medicine. The clinical efficacy, Hp eradication rate, symptom improvement and adverse reactions of the two groups were compared. Results The treatment effective rate of the observation group was 96.88%, which was significantly higher than that of the control group（78.91%）. The difference was statistically significant（P〈0.05）. The Hp eradication rate of the observation group was 87.50%, which was significantly higher than that of the control group（71.09%）, with statistically significant difference（P〈0.05）. TCM syndrome scores such as stomach cramps, upper abdominal pain, nausea and vomiting, mouth bitter and bad breath were significantly lower in the observation group than those in the control group, and the difference was statistically significant（P〈0.05）. The incidence of adverse reactions such as chest tightness, dizziness, fatigue, diarrhea and rash in the observation group was significantly lower than that in the control group, and the difference was statistically significant（P〈0.05）. Conclusion The combination of traditional Chinese and western medicine for the treatment of spleen and stomach damp heat type chronic gastritis combined with Hp infection is effective, which can improve the eradication effect of Hp, promote symptom relief, with low adverse reactions incidence, and has positive clinical significance.

关 键 词：慢性胃炎 HP感染 脾胃湿热型 中西医结合治疗 疗效分析 

分 类 号：R259[医药卫生—中西医结合] R573.3[医药卫生—中医内科学]