营养因子对非反刍动物肠道黏膜免疫的调控作用  

Regulation of Nutrition Factors on Intestinal Mucosal Immunity of Non-Ruminant Animals

作　　者：梁静[1] 张文举[1] 聂存喜[1] 寇莎莎 LIANG Jing;ZHANG Wenju;NIE Cunxi;KOU Shasha(College of Animal Science and Technology,Shihezi University,Shihezi 832000,China)

机构地区：[1]石河子大学动物科技学院,石河子832000

出　　处：《动物营养学报》2018年第11期4302-4311,共10页CHINESE JOURNAL OF ANIMAL NUTRITION

基　　金：兵团应用基础研究项目(2016AG009);石河子大学高层次人才科研启动项目(RCZX201503);国家自然科学基金(31760686)

摘　　要：肠道具有将肠腔内容物与机体内环境隔离的功能,防止致病性抗原(肠腔内细菌、有毒物质、食物抗原等)侵入黏膜下层组织,从而维持机体内环境的相对稳定。这一过程中黏膜防御体系起到了至关重要的作用。本文主要就肠道黏膜免疫系统组成结构、分类、主要免疫因子以及营养因子对肠道黏膜免疫的调控作用进行综述,旨在为营养素和非营养素对非反刍动物肠道免疫机能及其免疫调节作用机制研究提供参考。The intestine has the function of isolating the contents of the intestine from environment in the body to prevent pathogenic antigens（intestinal bacteria,toxic substances,food antigens,etc.） from invading submucosal tissues,thereby maintaining the relative stability of environment in the body.The mucosa defense system plays a crucial role in this process.This review focused on the intestinal mucosal immune system composition,classification,major immune factors,and the immunomodulatory effects of nutrition factors on intestinal mucosal immunity,aiming to provide reference for the intestinal immune function and immune regulation mechanism of nutrient and non-nutrients on non-ruminant animals.

关 键 词：非反刍动物 肠道黏膜 免疫因子 免疫机制 营养因子 

分 类 号：S852.2[农业科学—基础兽医学]