基于关联规则算法的慢性阻塞性肺疾病及其协同发病分析  

Association analysis of chronic obstructive pulmonary disease based on association rule

作　　者：贺建峰[1] 姚旭升 杨静[1] 谢颖夫 HE Jianfeng;YAO Xusheng;YANG Jing;XIE Yingfu(Faculty of Information Engineering and Automation,Kunming University of Science andTechnology,Kunming 65050)

机构地区：[1]昆明理工大学信息工程与自动化学院,昆明650504

出　　处：《北京生物医学工程》2018年第6期618-623,630,共7页Beijing Biomedical Engineering

基　　金：国家自然科学基金(11265007)资助

摘　　要：目的研究慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)的发病规律及与其他疾病的协同发病现象,为COPD的主动预防提供数据支持。方法采用统计分析及关联规则挖掘对云南省某三甲医院2013～2015年的住院病案首页数据中的COPD案例进行分析,研究COPD患者的共同特征。采用经典的APRIORI关联规则算法在MODELER软件中建模,研究COPD和其他疾病的协同发病规律。结果 COPD患者年龄集中在61岁以上(83. 9%),职业集中在离退休人员(59. 5%),男性偏多(80. 3%);关联规则挖掘结果中COPD和高血压同时发生的有3 834例,支持度45. 2%。COPD和慢性肺源性心脏病同时发生的实例有3766,支持度44. 4%。COPD和冠状动脉粥样硬化心脏病同时发生的有2 001例,支持度23. 6%结论 COPD高危人群为61岁以上的男性离退休人员,与COPD协同发病的疾病频率最高的为高血压、慢性肺源性心脏病等心脑血管疾病,这对主动预防和治疗COPD和相关疾病具有重要作用,同时也对研究疾病间的协同发病现象提供思路,可以推广到其他疾病的研究。Objective This study investigates the incidence of chronic obstructive pulmonary disease（ COPD ） and its synergistic effects with other diseases, and provides data support for proactiveprevention. Methods We analyze the first page data in medical records of COPD inpatients in a hospital ofYunnan Province in 2013 - 2015, and study the common characteristics of COPD patients with statisticalanalysis and association rule mining. In the MODELER software modeling, the classic APRIORI associationrules algorithm is used to study the synergistic incidence of COPD and other diseases. Results The ages ofCOPD patients focus on over 61 years （ 83. 9%）, occupation focus on retirees （ 59. 5%）, and most of theCOPD patients are male （80. 3%）. Association rule mining results show that COPD and hypertension occur in3 834 cases, the support degree is 45. 2%, COPD and chronic pulmonary heart disease occur in 3 766 cases,the support degree is 44. 4%, and COPD and coronary atherosclerotic heart disease occurr in 2001 cases, the support degree is 23. 6%. Conclusions COPD high.riskgroup are men, over the age of 61, retirees. The diseasessynergistic with COPD in the highest frequency arecardiovascular and cerebrovascular diseases, such as hypertension and chronic pulmonary heart disease, which is helpful to actively prevent and treat COPD andrelated diseases. This paper also provides a method for the research of synergistic effects and other diseases.

关 键 词：慢性阻塞性肺疾病 高血压 脑血管疾病 数据挖掘 关联规则 

分 类 号：R318[医药卫生—生物医学工程]