介入治疗对心肌病合并心肌梗死患者的心室功能和凝血指标的改善作用  

Effect of Interventional Therapy on Ventricular Function and Coagulation Parameters in Patients with Cardiomyopathy and Myocardial Infarction

作　　者：张辉[1] 陈超[1] 曹喆[1] 刘金良 常娟[1] 陈曼华[1] ZHANG Hui;CHEN Chao;CAO Zhe;LIU Jin-liang;CHANG Juan;CHEN Man-hua(Wuhan Central Hospital,Department of Cardiology of Hubei,Wuhan,430016,China)

机构地区：[1]武汉市中心医院心内科,武汉430016

出　　处：《血栓与止血学》2018年第4期571-573,共3页Chinese Journal of Thrombosis and Hemostasis

摘　　要：目的探讨介入治疗对心肌病合并心肌梗死患者的心室功能和凝血指标的改善作用。方法选取2016年1月至2017年5月在我院进行治疗的心肌病合并心肌梗死患者106例,根据数字表法随机分为观察组和对照组,每组各53例。对照组采用溶栓治疗方法,观察组采用PCI联合溶栓治疗方法。对两组治疗后的左心室功能指标变化进行比较与分析,对两组患者治疗后凝血指标比较与分析,对两组患者不良反进行比较分析。结果治疗前LVEDVI、LVESVI、LVEDD、IVST和LVPWT所有参数均无显著差异(P> 0. 05),治疗后,观察组所有参数均显著改善(P <0. 05),对照组仅LVEDVI、LVESVI指标具有显著改善(P <0. 05),观察组的改善程度均显著高于对照组(P <0. 05)。两组患者所有凝血相关指标检测仅D-D升高,对照组>观察组(P <0. 05);其它数据均在正常值范围,无实际临床意义。观察组并发症的总发生率和死亡率分别为1. 89%、5. 66%,显著低于对照组(9. 43%、13. 21),(P <0. 05)结论介入治疗在心肌病合并心肌梗死患者的治疗中能有效改善患者的心功能指标和降低并发症的发生。Objective To investigate the effect of interventional therapy on ventrieular function and coagulation parameters in patients with eardiomyopathy and myocardial infarction. Methods 106 patients with eardiomyopathy and myocardial infarction treated in our hospital from January 2016 to May 2017 were randomly divided into the observation group and the control group, with 53 cases in each group. The control group was treated with thrombolytie therapy, and the observation group was treated with PCI combined with thrombolytie therapy. The changes of left ventrieular function indexes after two groups of treatment were compared and analyzed, The blood coagulation indexes of the two groups were compared and analyzed. The adverse reaefionswere compared. Results Before treatment,LVEDVI,LVESVI,LVEDD, IVST and LVPWT all parameters showed no significant difference （ P 〉 0. 05 ） , after treatment, the observation group all parameters were significantly improved （P 〈 0. 05 ）, the control group only LVEDVI, LVESVI index has improved significantly（P 〈 0.05 ）, group comparison showed that the concept of degree of observation group were significantly improved higher than that of the control group（P 〈0.05）. All the clotting related indexes in the two groups were only increased in D-D, while those in the control group were significantly higher than those in the control group （P 〈 0.05 ）, and the other data were in the normal range and had no practical clinical significance. To observe the incidence and mortality of complications were 1.89% and 5.66%, significantly lower than the control group （ 9.43%, 13.21 ）, （ P 〈 0. 05 ）. Conclusion Interventional therapy combined with treatment of patients with acute myocardial infarction can effectively improve the patient＇ s heart function and reduce the incidence of complications.

关 键 词：介入治疗 心肌病 心肌梗死 凝血指标 

分 类 号：R542.2[医药卫生—心血管疾病]