运用脊髓伤方治疗脊髓型颈椎病的临床研究  

Clinical Study of Jisuishang Formula in Treatment of Cervical Spondylotic Myelopathy

作　　者：钟远鸣[1] 许伟[2] 李智斐[1] 付拴虎 莫日养 梁梓扬 ZHONG Yuanming;XU Wei;LI Zhife？;FU Shuanhu;MO Riyang;LIANG Ziyang(Department of Orthopedics,The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine,Nanning 530000,Guangxi,China;Graduate Department of Guangxi University of Traditional Chinese Medicine,Nanning 530000,Guangxi,China)

机构地区：[1]广西中医药大学第一附属医院骨一科,广西南宁530000 [2]广西中医药大学研究生学院,广西南宁530000

出　　处：《辽宁中医杂志》2018年第10期2133-2136,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：广西壮族自治区自然基金项目(QJJ14035);国家自然科学基金(81760874)

摘　　要：目的：观察中药脊髓伤方对脊髓型颈椎病患者术后神经功能恢复的影响,并进一步探讨其作用机制。方法：纳入2012年7月—2016年6月本科行手术治疗的脊髓型颈椎病气虚血瘀证患者57例,依据是否服用中药脊髓伤方分为两组：对照组（A组,n=22）术后常规应用糖皮质激素抗炎消肿,实验组（B组,n=35）在常规应用糖皮质激素的基础上服用中药脊髓伤方治疗。观察两组患者术前及术后第1、6、12个月颈椎JOA评分,计算术后第12个月的神经功能改善率;并于术后第12个月使用中医疾病疗效判定标准对所有患者进行疗效判定。结果：两组术前、术后第1个月比较颈椎JOA评分差异无统计学意义（P〉 0. 05）,两组术后第6、12个月比较JOA评分差异均有统计学意义（P 〈0. 05）,两组术后第12个月比较神经功能改善率、中医疾病疗效差异均有统计学意义（P 〈0. 05）。结论：中药脊髓伤方可有效促进脊髓型颈椎病患者术后神经功能恢复,显著改善其临床症状。Objective： To assesse the efficacy of Jisuishang Formula（JSSF） on the neurological function recovery in postoperated patients with cervical spondylotic myelopathy（CSM） and furtherly explore its mechanism. Methods： Fifty-seven postoperated cases with CSM,who belonged to Qi deficiency and blood stasis syndrome,were included from July 2012 to June 2016 in our department. All the patients were divided into two groups according to whether took the traditional Chinese medicine of JSSF. The group A（controlling group,n = 22） were regularly treated with glucocorticoid for anti-inflammation and detumescence after operation. The group B（tasting group,n = 35） also took the traditional Chinese medicine of JSSF after operation besides the treatment as in group A. The JOA scores of all patients were assessed before operation and at the first,sixth and twelfth month after operation. The rates of neurological function improvement were calculated at the twelfth month after operation and the efficacy of all patients was determinated at the twelfth month after operation. Results： There was no significant difference on scores of JOA between two groups before operation and at the first month after operation（P〈0.05）,while the differences were statistically significant at the sixth and twelfth month after operation（P〈0.05）. There were also significant difference on the rates of neurological function improvement and efficacy between two groups at the twelfth month after operation（P〈0.05）. Conclusion： The recovery of neurological function could be effectively promoted by JSSF in postoperated patients with CSM and their clinical symptoms were significantly improved.

关 键 词：脊髓型颈椎病 气滞血瘀证 脊髓伤方 神经功能 

分 类 号：R681.55[医药卫生—骨科学]