83例空泡蝶鞍综合征的临床分析  被引量:5

Clinical analysis and identification of 83 cases of empty sella syndrome

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作  者:刘星[1] 曹翠苹[2] 张海燕[2] 刘国良[2] LIU Xing;CAO Cui-ping;ZHANG Hai-yan(Department of endocrinology,The First Affiliated Hospital of China Medical University,Shenyang 110001,China)

机构地区:[1]鞍山钢铁集团公司总医院,辽宁鞍山114008 [2]中国医科大学附属第一医院,辽宁沈阳110001

出  处:《中国实验诊断学》2018年第11期1900-1902,共3页Chinese Journal of Laboratory Diagnosis

摘  要:目的提高空泡蝶鞍综合征(ESS)识别率。方法对本院2004年至2009年门诊、住院的经CT或/和MRI确诊的空泡蝶鞍综合征83例患者的临床、实验室、内分泌激素测定及影像检查的资料,进行回顾性的对比分析。结果(1)ESS年发现数13.83个,占同期垂体占位病变的5.47%;(2)女:男为54:29,女性均龄(47.3±11.6)岁,男性(43.7±15.3)岁;(3)影象检查:蝶鞍扩大占95.78%;垂体受压变扁56.43%,垂体未显示40.96%;垂体柄延长者18.07%,偏移者10.84%;脑脊液充填93.98%;(4)临床表现:头痛、视物异常占33.73%;垂体功能减退症59.04%;意外发现25.30%;溢乳者13.25%;(5)本组提示多孕妇、产后大出血似有明确关系;(6)内分泌激素水平,单一激素缺乏13.25%,部分缺乏43.37%,后叶缺乏7.23%,以ACTH(42.17%)、GnH(39.76%)、TSH(22.89%)缺乏为多。结论 ESS是一常见病,临床识别率较低,MRI是确诊的最佳方式。Objective To increase identification of empty sella syndrome(ESS)via summarizing the past.MethodsA retrospective analysis of the clinical,laboratory,hormone assays,and imaging data was carried in 83 patients with ESS who was diagnosed via CT or/and MRI images from 2004 to 2009 in China Medical University.Results(1)The incidence of ESS was 13.83 cases/year,was 5.47% of pituitary tumors at the same period.(2)the ratio of female vs male was 54:29.average ages of female were 47.3±11.6,average ages of male were 43.7±15.3;(3)Imaging medicine:sella extension was 95.78%,flat pituitary was 56.43%,no obvious pituitary image was 40.96%;extension of pituitary stalk was 18.07%,skewing was 10.84%;cerebrospinal fluid filling was 93.98%.(4)clinical symptoms:headache and abnormal vision was 33.73%;hypopituitary function was 59.04%;diagnosed accidentally was 25.30%;galactorrhea was 13.25%;(5)the current study suggests that multipregnancy,postpartum hemorrhage may likely be ascribed to ESS.(6)hormone levels:deficiency of single hormone was 13.25%,partial deficiency was 43.37%,deficiency of posterior hormones was 7.23%,most popular deficiency was observed in ACTH(42.17%),GnH(39.76%),TSH(22.89%).Conclusion ESS is a common disease,the clinical diagnostic rate is low,MRI is the most optimal method for its diagnose.

关 键 词:空泡蝶鞍综合征 提高识别率 MRI 

分 类 号:R817.4[医药卫生—影像医学与核医学]

 

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