化湿和胃汤联合西药治疗慢性胃炎(脾虚湿阻)随机平行对照研究  

Randomized Controlled Parallel Study of Huashi Hewei Decoction(化湿和胃汤) combined with Western Medicine in Treating Chronic Gastritis(Spleen Deficiency and Dampness Obstruction/脾虚湿阻)

作　　者：徐舟 XU Zhou(Huangshi Youse Hospital,Huangshi 435005,Hubei,China)

机构地区：[1]黄石有色医院中医内科,湖北黄石435005

出　　处：《实用中医内科杂志》2018年第9期25-27,共3页Journal of Practical Traditional Chinese Internal Medicine

摘　　要：[目的]观察化湿和胃汤联合西药治疗慢性胃炎(脾虚湿阻)疗效。[方法]使用随机平行对照方法,将200例住院患按病志号抽签方法方法随机分为两组。对照组100例奥美拉唑,20mg/次,1次/d;多潘立酮,10mg/次,3次/d。治疗组100例化湿和胃(芦根、姜~生、陈皮、苍术、桔梗、白术、佩兰各15g,神曲、半夏、茯苓、砂仁、厚朴、藿香、滑石、白芷各10g,黄连5g),水煎600mL,1剂/d,早晚分服,300mL/次;大便稀溏,加白术~炒15g;严重便秘,加白术~生12g;严重呕吐,加半夏10g;兼气滞胀满,减少白术用量,加莱菔子15g,枳壳10g;明显发热,减少半夏用量,加黄连5g,砂仁10g;夜间睡眠差,加酸枣仁15g;饮食较差,加焦三仙15g;明显反酸,加乌贼骨15g,瓦楞子20g;西药治疗同对照组。连续治疗4周为1疗程。观测临床表现、中医证候积分、不良反应。治疗1疗程(4周),判定疗效。[结果]治疗组显效53例,有效44例,无效3例,总有效率97.00%;对照组显效49例,有效41例,无效10例,总有效率90.00%;治疗组疗效优于对照组(P<0.05)。中医证候评分两组均有改善(P<0.01),治疗组改善优于对照组(P<0.01)。不良反应治疗组低于对照组(P<0.05)。[结论]化湿和胃汤联合西药治疗慢性胃炎(脾虚湿阻),疗效满意,无严重不良反应,值得推广。[Objective] To observe the therapeutic effect of Huashi Hewei decoction（化湿和胃汤） combined with western medicine on chronic gastritis（spleen deficiency and dampness obstruction）. [Methods]200 hospitalized patients were randomly divided into two groups according to the method of drawing lots according to their medical records. In the control group, 100 cases were omeprazole, 20 mg/times, 1 times/d, domperidone, 10 mg/times, 3 time/d. In the treatment group, 100 cases were treated with Huashi Hewei decoction（Lugen, Shengjiang,Chenpi,Cangzhu, Jiegeng, Baizhu, Peilan each 15 g, Shenqu, Banxia, Fuling,Sharen, Houpo, Huoxiang, Huashi, Baizhi each 10 g, Huanglian 5 g）, decocted 600 mL, one dose per day, taken separately in the morning and evening, 300 mL/time, diluted stool, stir-fried with Chaobaizhu 15 g; severe constipation add Shengbaizhu 12 g; vomit add Banxia 10 g; both qi stagnation and fullness, reduce the dosage of atractylodes macrocephala, plus Laifuzi 15 g, Zhiqiao 10 g; fever, reduce the dosage of pinellia ternata, add Huanglian 5 g, Sharen 10 g; poor night sleep, add Suanzaoren 15 g; poor diet, add Jiaosanxian 15 g; obvious acid reflux, add sepia bone 15 g, corrugated seeds 20 g; western medicine treatment Same control group. Continuous treatment for 4 weeks was 1 courses. Observation of clinical manifestations, TCM syndrome scores, adverse reactions. The course of treatment was 1 weeks（4 weeks）, and the curative effect was judged. [Results] In the treatment group, 53 cases were markedly effective, 44 cases were effective, 3 cases were ineffective, the total effective rate was 97.00%; in the control group, 49 cases were markedly effective, 41 cases were effective,10 cases were ineffective, the total effective rate was 90.00%; the curative effect of the treatment group was better than that of the control group（P〈0.05）. TCM syndrome scores in the two groups were improved（P〈0.01）, and the improvement in the treatment group was better than that in the control group（P〈0.01

关 键 词：慢性胃炎 胃脘痛 胃痞 化湿和胃汤 藿香正气散 奥美拉唑 多潘立酮 中医证候积分 中药复方 随机平行对照研究 

分 类 号：R259[医药卫生—中西医结合]