Three new diterpenoid alkaloids isolated from Aconitum brevicalcaratum  

作　　者：SHU Yan YIN Tian-Peng WANG Jia-Peng GAN Dong ZHANG Qin-Yan CAI Le DING Zhong-Tao SHU Yan;YIN Tian-Peng;WANG Jia-Peng;GAN Dong;ZHANG Qin-Yan;CAI Le;DING Zhong-Tao(Functional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, School of Chemical Science and Technology, Yunnan University;Zhuhai Key Laboratory of Fundamental and Applied Research in Traditional Chinese Medicine, Zunyi Medical University Zhuhai Campus)

机构地区：[1]Functional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, School of Chemical Science and Technology, Yunnan University [2]Zhuhai Key Laboratory of Fundamental and Applied Research in Traditional Chinese Medicine, Zunyi Medical University Zhuhai Campus

出　　处：《Chinese Journal of Natural Medicines》2018年第11期866-870,共5页中国天然药物（英文版）

基　　金：financially supported by the National Natural Science Foundation of China(No.81460648);Guizhou Science and Technology Foundation of China(No.QKHJC[2018]1193);Yunling Scholars of Yunnan province,and Program for Excellent Young Talents,Yunnan University

摘　　要：In the present study, three new aconitine-type diterpenoid alkaloids brochyponines A–C(1–3) were isolated from the roots of Aconitum brevicalcaratum. Their structures were established on the basis of extensive spectroscopic analyses(IR, HR-ESI-MS, and 1D and 2D NMR). The NMR data of salt form for compound 1 in CDCl_3 were also measured.In the present study, three new aconitine-type diterpenoid alkaloids brochyponines A–C（1–3） were isolated from the roots of Aconitum brevicalcaratum. Their structures were established on the basis of extensive spectroscopic analyses（IR, HR-ESI-MS, and 1D and 2D NMR）. The NMR data of salt form for compound 1 in CDCl3 were also measured.

关 键 词：Aconitum brevicalcaratum RANUNCULACEAE Diterpenoid alkaloid Brochyponine 

分 类 号：R284.1[医药卫生—中药学]