瑞芬太尼和丙泊酚合剂全凭静脉麻醉用于腹腔镜辅助直肠癌根治术的配比观察  

Proportioning observation of total intravenous anesthesia with remifentanil and propofol mixture for laparoscopic-assisted radical resection of rectal cancer

作　　者：哈斯 周颖[2] 杜浩 云晓芳 HA Si;ZHOU Ying;DU Hao(Department of Anesthesia,Inner Mongolia Hohhot Mongolian Medicine Hospital of traditional Chinese Medicine,Hohhot 010010,China)

机构地区：[1]内蒙古呼和浩特市蒙医中医医院手术麻醉科,010010 [2]武警内蒙古总队医院麻醉科,010000

出　　处：《中国实用医药》2018年第33期89-90,共2页China Practical Medicine

摘　　要：目的探讨瑞芬太尼和丙泊酚合剂全凭静脉麻醉用于腹腔镜辅助直肠癌根治术不同配比的麻醉效果。方法 40例腹腔镜辅助直肠癌根治术患者,随机分为Ⅰ组和Ⅱ组,每组20例。两组诱导方式相同,Ⅰ组以5%葡萄糖注射液500 ml加2.0 mg瑞芬太尼与800 mg丙泊酚的合剂全凭静脉麻醉。Ⅱ组以5%葡萄糖注射液500 ml加1.0 mg瑞芬太尼与600 mg丙泊酚的合剂全凭静脉麻醉。比较两组清醒时间和拔管时间。结果Ⅰ组患者清醒时间(5.51±2.32)min、拔管时间(5.70±2.37)min短于Ⅱ组的(8.20±2.55)min、(8.80±3.53)min,差异有统计学意义(P<0.05)。两组躁动发生率比较差异无统计学意义(P>0.05)。结论 5%葡萄糖注射液500 ml加2.0 mg瑞芬太尼与800 mg丙泊酚的合剂全凭静脉麻醉方式效果更加优越,术中麻醉平稳,术后患者清醒迅速,更适合于腹腔镜辅助直肠癌根治术的麻醉。Objective To discuss the anesthetic effect of total intravenous anesthesia with remifentanil and propofol mixture in different proportions for laparoscopic-assisted radical resection of rectal cancer. Methods A total of 40 patients with laparoscopic-assisted radical resection of rectal cancer were randomly divided into group Ⅰ and group Ⅱ, with 20 cases in each group. The induction methods of the two groups were the same. Group I was anesthetized by total intravenous anesthesia with 500 ml 5% glucose injection, 2.0 mg remifentanil and 800 mg propofol. Group Ⅱ was anesthetized by total intravenous anesthesia with 500 ml 5% glucose injection, 1.0 mg remifentanil and 600 mg propofol. The awake time and extubation time between the two groups was compared. Results Group Ⅰ had awake time as（5.51±2.32） min and extubation time as（5.7±2.37） min, which were all lower than（8.20±2.55） min and（8.8±3.53） min in group Ⅱ, and their difference was statistically significant（P〈0.05）. There was no statistically significant difference in incidence of restlessness（P〈0.05）. Conclusion Total intravenous anesthesia with 500 ml 5% glucose injection, 2.0 mg remifentanil and 800 mg propofol is more effective with stable anesthesia during operation and rapid awakening after operation, so it is more suitable for anesthesia of laparoscopic-assisted radical rectal cancer.

关 键 词：瑞芬太尼 丙泊酚 合剂 腹腔镜 直肠癌根治术 

分 类 号：R614.24[医药卫生—麻醉学]