自闭症谱系障碍与维生素D的流行病学研究进展  

Current epidemiological study on autism spectrum disorder and vitamin D

作　　者：无 贾妮[2] 戴耀华[2] China Preventive Medicine Assocition;Society of Child Health

机构地区：[1]中国预防医学会儿童保健分会 [2]首都儿科研究所

出　　处：《中国妇幼健康研究》2018年第11期1357-1360,共4页Chinese Journal of Woman and Child Health Research

摘　　要：很多研究显示,自闭症谱系障碍(ASD)在我国儿童中患病率呈上升趋势,但我国仍需要筛查和诊断方法统一的大范围流行病学调查。现有证据表明,ASD儿童的血清维生素D(VitD)水平较正常儿童低,儿童VitD水平与ASD诊断量表评分之间存在相关关系。对于母亲孕期VitD水平与儿童ASD相关的人群研究很多都是阴性结果,但也有控制混杂因素的阳性研究结果。近期很多研究也显示,孕期补充VitD,能减少儿童ASD患病率;儿童补充VitD,对改善儿童ASD症状有帮助。此外,很多流行病学研究显示,ASD与导致VitD缺乏的光照环境因素相关。Numerous studies have shown that the prevalence rate of autism spectrum disorder（ASD）tends to rise in China,but it＇s still necessary to conduct a wide epidemiology survey based on standard screening and diagnostic methods.Evidence showed that ASD children had lower vitamin D（VitD）levels than normal children,and VitD levels were related to scores of ASD diagnosis scales.Maternal VitD status was not related to ASD in offspring in many studies,but an increasing amount of evidence pointed to the possibility that gestational VitD deficiency caused some cases of autism.Recently researches reported that maternal VitD supplements could reduce prevalence rate of offspring with ASD,and VitD supplements to children with ASD was benificial to improving ASD syndromes.Moreover,many epidemiological studies have shown that ASD is correlated with illumination environmental causing VitD deficiency.

关 键 词：自闭症谱系障碍 维生素D 流行病学 自闭症 

分 类 号：R179[医药卫生—妇幼卫生保健]