新生儿先天性喉喘鸣患儿病因分析及其治疗研究  

Analysis of etiology and treatment of neonatal congenital throat wheezing

作　　者：陶礼华[1] 黄敏[1] 李赟[1] 赵斯君[1] TAO Li-hua;HUANG Min;LI Yun;ZHAO Si-jun(Hunan Children＇s Hospital,Changsha,Hunan 410007)

机构地区：[1]湖南省儿童医院,湖南长沙410007

出　　处：《中国优生与遗传杂志》2018年第11期88-90,104,共4页Chinese Journal of Birth Health & Heredity

摘　　要：目的探讨新生儿先天性喉喘鸣患儿病因分析及其治疗方法。方法本研究对象系新生儿,主诉为喉喘鸣,时间系2011年01月至2016年12月来我院就诊的852例新生儿,通过奥林巴斯超细电子鼻咽喉镜检查,对检查数据进行回顾性研究,并对预后影响因素进行分析。结果 852例喉喘鸣患儿中,男498例(58.45%),女354例(41.55%)。其中先天性喉软化的患儿有689例,占(80.87%);喉囊肿有85例,占(9.98%);声带运动障碍有36例,占(4.23%);急性喉炎有16例,占(1.88.%);喉噗有14例,占(1.64%);血管瘤有6例,占(0.70%);喉裂有3例,占(0.35%);声门下狭窄有2例,占(0.23%);后鼻孔不全闭锁有1例,占(0.12%)。新生儿先天性喉喘鸣患儿预后不良与性别、体重、感染、输血、确诊时间、喉软化、声带运动障碍、急性喉炎、喉裂及声带下狭窄有关(P<0.05),与日龄、住院时间、抗感染药物使用、手术均无显著关系(P>0.05)。多因素分析结果显示体重、感染、确诊时间及喉软化为新生儿先天性喉喘鸣患儿预后不良的独立性影响因素(P<0.05)。结论先天性喉软化症为婴儿喉喘鸣的主要病因.其次为占位性病变、炎症、声带运动障碍、气道结构异常等,先天性喉软化症患儿预后不良与体重、感染、确诊时间及喉软化有关。Objective： To investigate the etiology and treatment of neonatal children with congenital laryngeal wheezing. Methods： This study was a neonate with a complaint of laryngeal wheezing. The time was from 852 newborns who came to our hospital from January 2011 to December 2016. Through Olympus ultra-fine electronic nasopharyngoscopy, Review the data for a retrospective study, and analyze the prognostic factors. Results： Of the 852 children with laryngeal wheezing, 498 were male （58.45%） and 354 were female （41.55%） .Among them, there were 689 children with congenital laryngeal softening, accounting for （80.87%） ： 85 cases with laryngeal cysts, accounting for （9.98%） ; 36 cases with vocal cord dyskinesia, accounting for （4.23%） ~ 16 cases with acute laryngitis, Accounted for （1.88.%） ~ 14 cases of throat, accounting for （1.64%） ： 6 cases ofhemangioma, accounting for （0.70%） ; 3 cases of laryngeal fissure, accounting for （0.35%） ： 2 cases of subglottic stenosis, Accounted for （0.23%） ： 1 case of inferior nostril insufficiency, accounting for （0.12%） . The death of neonates with congenital laryngeal wheezing was related to gender, weight, infection, blood transfusion, time of diagnosis, laryngeal softening, vocal cord dyskinesia, acute laryngitis, laryngeal fissure and vocal stenosis （P〈0.05） , and age, There was no significant relationship between hospitalization time, anti-infective drug use and surgery （P〉0.05） .Multivariate analysis showed that body weight, infection, time of diagnosis and laryngeal softening were independent factors influencing the prognosis of neonates with congenital laryngeal wheezing （P〈0.05） . Conclusion： Congenital laryngeal softening is the main cause of infant throat wheezing. Followed by space-occupying lesions, inflammation, vocal cord dyskinesia, airway structural abnormalities, etc., poor prognosis in children with congenital laryngeal softening is related to body weight, infection, time of diagnosis and thr

关 键 词：新生儿 先天性喉喘鸣 病因 治疗 

分 类 号：R722.1[医药卫生—儿科]