疏毛罗勒多糖对小鼠腹腔巨噬细胞吞噬活力的影响  

Effect of polysaccharide from Ocimum basilicum Linn var.ppilosum(wild.) Benth on rat peritoneal macrophages

作　　者：张秋妍[1,2] 赵静[1] 孙晶晶 张芙蓉 赵海君 屈长青[1,2] ZHANG Qiuyan;ZHAO Jing;SUN Jingjing;ZHANG Furong;ZHAO Haijun;QU Changqing(School of Biological and Food Engineering;Engineering Technology Research Center of Anti-aging Chinese Herbal Medicine,Fuyang Anhui 236037,China)

机构地区：[1]阜阳师范学院生物与食品工程学院,安徽阜阳236037 [2]阜阳师范学院抗衰老中草药安徽省工程技术研究中心,安徽阜阳236037

出　　处：《阜阳师范学院学报（自然科学版）》2018年第4期49-51,62,共4页Journal of Fuyang Normal University(Natural Science)

基　　金：安徽省教育厅自然科学研究重点项目(KJ2016A872;KJ2016A871);安徽高校科研平台创新团队建设项目(XDHXPT201703);安徽省省级科研平台委托专项项目(2014KSLZX01ZD)资助

摘　　要：提取疏毛罗勒多糖,研究不同浓度疏毛罗勒多糖对小鼠腹腔巨噬细胞吞噬活力的影响。用不同浓度罗勒多糖(50μg·mL-1、100μg·mL-1、150μg·mL-1)处理小鼠腹腔巨噬细胞,用中性红法测定罗勒多糖对巨噬细胞的吞噬活力。结果显示:随着罗勒多糖浓度的升高,巨噬细胞的吞噬活力增强,当罗勒多糖浓度达到100μg·mL-1时,与对照组相比达到极显著水平(P<0.01)。综上所述,罗勒多糖可增强小鼠腹腔巨噬细胞的吞噬能力。To explore the effects of basil polysaccharide（BPS） by rat peritoneal macrophage in vitro. Macrophages were separated from the peritoneal of mice and were cultured with different concentration of BPS（50 μg ·mL^- 1, 100 μg ·mL^- 1, 150 μg · mL-1）. Neutral red method was used to examine the phagocytosis. The phagocytosis of mouse peritoneal macrophages can be enhanced with the rise of BPS concentration. When BPS concentration is up to 100 μg · mL^- 1, compared with the control group reaches a significant level. BPS can improve the phagocytic activity of mouse peritoneal macrophages.

关 键 词：罗勒多糖 小鼠 腹腔巨噬细胞 吞噬活力 

分 类 号：R285.5[医药卫生—中药学]