新型尿素吸附剂的制备及其对血液中BUN吸附性能分析  

Preparation and Properties of a New Alginate-Zn Complex for Absorbing BUN in Blood

作　　者：于美丽[1] 宋继昌[1] 孙铭[1] 许有华[1] 郑惠英[1] 吕文岚[1] 付丽[1] 王勇 

机构地区：[1]天津市第三中心医院肝胆疾病研究所,300170 [2]天津市复印技术研究所,300130

出　　处：《北京生物医学工程》2002年第3期226-229,共4页Beijing Biomedical Engineering

摘　　要：首次采用海藻酸锌络合物配位吸附尿素分子 ,研究了这类络合物在不同条件下对尿素的吸附性能。结果表明海藻酸锌络合物对尿素的吸附主要是通过锌与尿素之间的配位作用进行的。在模拟人体生理介质的水溶液中对尿素的吸附率达 74 6 5± 4 71% ,对血液中尿素的吸附率达 6 5 2 5± 4 33%。New type Alginate Zn complex beads were prepared for removing of urea moleculars for the first time.Characteristics of urea adsorption under different conditions were discussed.Results showed that Alginate Zn complex adsorbed urea by means of coordination effect between zinc and urea.The adsorption efficiency of the complexe was determined to be 74 65±4 71% in a buffer of Na 2 HPO 4 NaH 2PO 4(pH=7 4)and to be 65 25±4 33% in blood.

关 键 词：尿素吸附剂 海藻酸锌络合物 配位吸附 尿素 

分 类 号：R318.16[医药卫生—生物医学工程]