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作 者:戴东[1] 谭小宇[1] 曾宪成[1] 杜松涛[1]
机构地区:[1]广东医学院附属医院外科,广东湛江524001
出 处:《中国普通外科杂志》2002年第8期473-475,共3页China Journal of General Surgery
基 金:.NULL.
摘 要:目的 探讨梗阻性黄疸病人围手术期肾功能的保护及急性肾功能衰竭(ARF)的预防。方法 观察组术前行短期肠外营养,术中、术后小剂量多巴胺持续静脉滴注,并定时快速滴注20%甘露醇。对照组采用常规处理方法。动态观察术后尿素氮(BUN)和肌酐清除率(Cr)的变化及ARF的发生率。结果 观察组术后各时相BUN和Cr明显低于对照组(P<0.05)。观察组25例中无1例发生ARF;对照组17例中5例(29.4%)发生ARF且有3例(17.6%)死亡(P<0.05)。结论 术前行短期肠外营养,术中及术后充足的组织灌流及充分利尿是预防梗阻性黄疸病人术后并发ARF的关键。<Abstrcat>ObjectiveTo investigate the protection of renal function and the prevention of acute renal failue(ARF) in perioperative period in obstructive jaundice(OJ) patients. Methods In experimantal group, short time parenteral nutrition(PN) was given preoperatirely.Small dosage of dopamine was intravenously dripped.and rapid infusion of 20% mannitol periodically was done.In control group routine treatment was done. Postoperative blood BUN and Cr dynamic changes were examined and occurrence rate of ARF were recorded. Results No ARF occurred in the experimental group;but ARF occurred in 5 cases(29.4%)and 2 cases(17.6%) died (P<0.05)in cotrol group. ConclusionsA short time preoperative PN, supporting sufficient tissue perfusion, enough diuretic therapy in intra and postoperation are key to prevent postoperative ARF in OJ patients.
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