急性脑外伤 TRH 兴奋试验改变及对伤情估价和预后判定的意义  

The significance of TRH provocation test in acute head injury

作　　者：滕良珠[1] 薛庆澄[1] 马丽云[2] 陈昆明[2] 王俊生[2] 孙贵连 

机构地区：[1]天津医学院附院神经外科 [2]天津医学院同位素室

出　　处：《中华神经外科杂志》1991年第3期179-183,共5页Chinese Journal of Neurosurgery

摘　　要：本文通过分析66例急性脑外伤病人和34例对照者的血清 TSH、PRL 和 GH 浓度变化及 TRH兴奋试验的改变,探讨 TRH 兴奋试验在急性脑外伤病人病情估计和预后判定方面的意义。发现:TRH 兴奋试验改变与病情和预后的不同有关。13例对 TRH 无反应者中,10例见于特重组,13例全部死亡。随着伤情的加重,预后的变坏,TSH、PRL 和 GH 浓度也越来越高,TSH 和 PRL 对 TRH的反应也越来越差。应用激素计分法判定预后,正确率为82%。作者认为 TRH 兴奋试验可作为估价病情,判定预后的指标。Serum TSH,PRL,GH,and TRH provocationtest were studied in 66 cases of acute head injuryand 34 controls.It was found that the serum TRHchanges were correlated with the severity of theinjuried patients.13 cases were not reacted to TRHprovocation.Among those patients GCS were 3-5in 10 cases,All of the 13 cases died.The moreseverity of the injury,the worse prognosis of thepatients.The level of TST,PRL and GH increasedresponse of TSH,PRL to TRH reduced.It maybe useful in making prognosis of acute head injury.The correct rate was 82%.

关 键 词：脑损伤 TRH兴奋试验 预后 

分 类 号：R651.15[医药卫生—外科学]