重度二尖瓣狭窄合并左心耳血栓患者的球囊扩张术研究  

Safety and efficacy of percutaneous balloon mitral valvuloplasty in patients with severe mitral stenosis and thrombus in the left atrial appendage

作　　者：李新明[1] 李斌[1] 陈关良[1] 苏哲坦[1] 张洁[2] 章志娟[2] 李小民[2] 旅朝霞[3] 方唯一[3] 于文信[3] 

机构地区：[1]海南省人民医院,海口570311 [2]徐州医学院附属连云港医院,222002 [3]大连医科大学第一附属医院,116011

出　　处：《海南医学》2002年第9期3-5,共3页Hainan Medical Journal

摘　　要：目的　评价经皮二尖瓣球囊扩张术 (PBMV)治疗重度二尖瓣狭窄合并左心耳血栓的可行性、安全性和有效性。方法　选择经华法令抗凝治疗 12周以上的重度二尖瓣狭窄合并左心耳部位血栓患者 11例 ,男性 2例 ,女性9例 ;平均年龄 40 .6± 5 .7(2 5～ 62 )岁。采用Inoue单球囊技术行PBMV。术后随访一年以上 ,观察术中及随访期间有无体循环血栓栓塞并发症。结果　手术成功率 10 0 % ,术中及随访期间无一例发生血栓栓塞并发症。术后即刻及随访期间血流动力学及心功能明显改善。结论　对于经适当的华法令抗凝治疗后的重度二尖瓣狭窄合并左心耳血栓的患者 ,PBMV不仅安全可行而且可取得满意的疗效。Objective:To evaluate the safety and efficacy of percutaneous balloon mitral valvuloplasty(PBMV) in patients with rheumatic severe mitral stenosis and thrombus in the left atrial appendage.Methods:We selected 11 patients with 9 women and 2 men,average 40.6±5.7(25～62)years old.All cases received warfarin orally every day for more than 12 weeks before underwent PBMV used Inoue single balloon technigue.Systemic thromboembolism complication were observed during operation and one year follow-up term.Results:The successful rate of PBMV was 100%.No systemic thromboembolism occurred during and after PBMV.The paraments of hemodynamics,mitral valve area and cardiac function improved markedly.Conclusion:The study showed that PBMV on the patient with severe mitral stenosis and thrombus in the left atrial appendage is safe and effective after certain anticoagulation treatment.

关 键 词：重度二尖瓣狭窄 左心耳血栓 二尖瓣球囊扩张术 合并症 临床研究 

分 类 号：R654.2[医药卫生—外科学]