止血灵胶囊质量标准的研究  

Studies on Quality Standard of Zhixueling Capsule

作　　者：罗轶 

机构地区：[1]广西壮族自治区药品检验所,广西南宁530021

出　　处：《中国实验方剂学杂志》2002年第5期8-9,共2页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：目的 :修订并提高止血灵胶囊的质量控制方法。方法 :用薄层色谱法对其中地榆、蒲公英进行了定性鉴别 ;用薄层光密度法对黄芪中有效成分进行了含量测定。结果 :表明本品定性鉴别色谱特征明显 ,易于区别 ;黄芪甲甙含量测定线性范围为0 6～ 3 6 μg ,平均回收率 10 2 6 8% ,RSD为 2 5 %。结论 :建立了该制剂的质量标准 ,其鉴别与含量测定方法简便、可靠、实用。Objective:a method for the quality control of Zhixueling capsule was modified and improved.Method: Radix sanguisorbae,Heaba taraxaci were identified by TLC.A method of thin layer densitometry to determine astragalin A,the main effective component from Radix astragali in the capsule,was developed.Result:The studies on the quality control showed that the characteristics for identification by TLC were distinct.The quantification method had the linear range of 0 6～3 6μg.The average recovery was 102 68% and its RSD was 3 2%.Conclusion:The quality standard of the capsule was modified and improved.The methods for identification and quantification were simple,reproducible and realizable.

关 键 词：止血灵胶囊 质量标准 黄芪甲甙 含量测定 薄层光密度法 

分 类 号：R286.0[医药卫生—中药学]