半导体纳米晶体的光致发光特性及在生物材料荧光标记中的应用  

Photoluminescence Properties of Semiconductor Nanocrystals and Their Applications in Biological Fluorescent Probes

作　　者：孙宝全[1] 徐咏蓝[2] 衣光舜[1] 陈德朴[1] 

机构地区：[1]清华大学化学系,北京100084 [2]石油大学化工学院环境中心,北京102200

出　　处：《分析化学》2002年第9期1130-1136,共7页Chinese Journal of Analytical Chemistry

基　　金：国家自然科学基金资助课题 (No .399890 0 1)

摘　　要：介绍了半导体纳米晶体 (亦称量子点 )的结构特征和光致发光特点 ,并与有机荧光染料分子的光致发光性质作了对比。结合本实验室所做的工作 ,对半导体纳米晶体用于生物材料的连接、标记和检测作了综述。Photoluminescence properties and biological application of semiconductor nanocrystals (also known as quantum dots) has been reviewed. Semiconductor nanocrystals exhibit a wide range of size-dependent properties. The semiconductor nanocrystals behave highly photochemical stability with a narrow, tunable, symmetric emission spectrum, a big Stokes' shift compared with conventional organic fluorophores. The advantages of the broad, continuous excitation spectrum were demonstrated in many biological fluorescent labels. These semiconductor nanocrystal probes are thus complementary and in some cases may be superior to existing fluorophores.

关 键 词：生物材料 荧光标记 光致发光特性 半导体纳米晶体 DNA 蛋白质 结构 临床检测 

分 类 号：O657.3[理学—分析化学]