鸡基底前脑胆碱能皮质投射神经元区的ChAT样免疫反应神经元  

Choline Acetyltransase-Like Immunoreactive Neurons in Cholinergic Cortical Projection Neuron Areas of the Basal Forebrain in the Hen

作　　者：陈正礼[1] 范光丽[1] 赵慧英[1] 邱荣斌[1] 王跃嗣[1] 白占涛[1] 

机构地区：[1]西北农林科技大学畜牧兽医学院,杨凌712100

出　　处：《畜牧兽医学报》2002年第5期454-457,共4页ACTA VETERINARIA ET ZOOTECHNICA SINICA

基　　金：国家自然科学基金 ( 396 70 5 5 0 )

摘　　要：应用免疫组织化学SP法 ,对 5只产蛋高峰期鸡基底前脑胆碱能皮质投射神经元区的ChAT样免疫反应神经元的分布特征进行了研究。结果发现 :从内侧隔核至Meynert基底核 ,ChAT样免疫反应神经元呈连续性分布 ,且各区神经元的密度、大小及着色强度不均。MS、NDBV/H及旧纹体膨大部的阳性细胞分布密集 ,且突起较明显 ;原始旧纹体部阳性细胞分布稀疏 ,突起明显。结果表明 ,在鸡的基底前脑胆碱能皮质投射神经元区广泛分布着ChAT样免疫反应神经元 ,这为鸡的基底前脑—海马投射系统积累了资料 ,表明该区在鸡的学习、记忆中起着重要的调节作用。The distribution of cholineacetyltransase-like immunoreactive(ChAT-LI)neurons in the basal forebrain cholinergic cortical neuron areas in the hen was studied by using the technique of immunohistochemistry SP.The results showed that a continuum of ChAT-LI neurons were distributed in the medial septal nucleus(MS),nuclei of diagonal band,vertical and horizonal divisions(NDBV/H),nucleus basalis of Meynert(NBM),but the density,size and staining of neurons in respectively areas weren′t even.In MS,NDBV/H and paleostriatum augmentatum(PSA),the neurons were high density and the dendrite were obviously detected,but the neurons were sparsely distributed in the paleostriatum primitivum(PSP).The above results demonstrate that the ChAT-LI neurons were widely distributed in the basal forebrain cholinergic cortical neurons areas in the hen,which accumulate the materials for the projection system of basal forebrain to hippocampus in the hen and suggest that basalforebrain cholinergic cortical areas play an important role in modulation of the learning and memory.

关 键 词：鸡 基底前脑胆碱能皮质投射神经元区 CHAT 免疫反应神经元 基底前脑 胆碱乙酰转移酶 免疫组织化学SP法 

分 类 号：S852.2[农业科学—基础兽医学] Q189[农业科学—兽医学]