低密度与高密度脂蛋白胆固醇比值对冠心病的诊断价值  

The Predictive Value of LDL-C/HDL-C Radio for Coronary Heart Disease Risk

作　　者：陈礼平[1] 曾春来[1] 王春明[1] 韦铁民[1] 赵瑞英[1] 吕干新[1] 吕玲春[1] 

机构地区：[1]浙江省丽水市中心医院心内科,323000

出　　处：《心脑血管病防治》2002年第3期11-12,共2页CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT

摘　　要：目的 探讨低密度脂蛋白胆固醇(LDL-C)和高密度脂蛋白胆固醇(HDL-C)浓度的比值与冠心病(CHD)的相关性。方法 对68例胸痛患者行冠状动脉造影,并同时测定其血脂成分。结果CHD组总胆固醇(TC)、血清甘油三酯(TG)、LDL-C、TC/HDL-C、TG/HDL-C、LDL-C/HDL-C高于对照组,HDL-C(低于对照组。LDL-C/HDL-C与CHD的相关性最强(OR=3.79,OR95％Cl=1.88-6.14)。结论 CHD患者存在多种血脂异常,LDL-C/HDL-C是一项有较好使用价值的CHD预测指标。Objective To evaluate the relationship between low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C) and coronary heart disease (CHD). Methods Coronary angiography was performed in 68 patients with chest pain, meanwhile, serum-lipid was measured in all these patients. Results Serum-cholesterol (TC),triglycende(TG),LDL-C,TC/HDL-C,TG/HDL-C and LDL-C/HDL-C radio were significantly higher in patients with CHD than those in normal controls (P<CO. 05), HDL-C was significantly lower in patients with CHD (P<0. 01). LDL-C/HDL-C ratio was significantly correlated with the incidence of CHD (OR = 3. 79, OR 95% CI = 1. 88--6. 14). Conclusions Some serum-lipid disorder was existed in patients with CHD. LDL-C/HDL-C ratio was a better predicting index for CHD risk.

关 键 词：低密度胆蛋白胆固醇 高密脂蛋白胆固醇 冠心病 诊断 冠状动脉疾病 CHD 

分 类 号：R541.4[医药卫生—心血管疾病]