化痰逐瘀解毒汤治疗强直性脊柱炎的临床观察  

Clinical Observation on Treatment of Ankylosing Spondylitis with Huatan Zhuyu Jiedu Decoction

作　　者：苗后清[1] 阎平[1] 刘书珍[2] 陈恩华[1] 路鸥[1] 刘星[1] 王益芝[1] 

机构地区：[1]山东省济宁市第一人民医院,山东272111 [2]山东省济宁市中医院

出　　处：《中国中西医结合杂志》2002年第8期574-576,共3页Chinese Journal of Integrated Traditional and Western Medicine

摘　　要：目的 :观察化痰逐瘀解毒汤治疗强直性脊柱炎的临床疗效。方法 :10 0例患者随机分为 2组 ,治疗组 6 0例 ,口服化痰逐瘀解毒汤煎剂 ;对照组 4 0例 ,口服独活寄生汤煎剂。 2组均水煎服 ,每日 1剂 ,1个月为 1个疗程 ,治疗 1～ 3个疗程统计疗效。结果 :治疗组近期控制 12例 ,显效 2 9例 ,好转 16例 ,无效 3例 ,总有效 5 7例 (95 % ) ;对照组近期控制 2例 ,显效 8例 ,好转 2 0例 ,无效 10例 ,总有效 30例 (75 % )。两组总有效率比较差异有显著性 (χ2 =2 0 85 ,P <0 0 1)。两组治疗后腰背痛显著减轻 ,脊柱运动功能 (前屈、后伸、侧弯 )均有显著改善 ,胸廓扩张度增加。血沉 (ESR)、补体 3(C3)、免疫球蛋白 (IgA)、C 反应蛋白 (CRP)显著下降 ,治疗前后上述指标比较差异有显著性 (P <0 0 5或P <0 0 1) ,但治疗组优于对照组 (P <0 0 5 )。两组治疗后X线片比较 ,治疗组改善 11例 ,对照组改善 4例 ,组间比较 ,差异有显著性 (χ2 =7 99,P <0 0 1)。结论 :化痰逐瘀解毒汤治疗强直性脊柱炎疗效确切。Objective: To observe the clinical effect of Huatan Zhuyu Jiedu Decoction (HZJD) in treating ankylosing spondylitis (AS). Methods: One hundred AS patients were randomly divided into two groups, the 60 patients in the treated group were treated with HZJD, the 40 patients in the control group were treated with Duhuo Jisheng Decoction. Treatment for both groups was orally given 1 dose per day in decoction form for 1 month as a treatment course. The efficacy of treatment was evaluated after 1-3 treatment courses. Results: The effect of treatment in the treated group was short term controlled in 12 patients, markedly effective in 29, improved in 16 and ineffective in 3, the total effective rate was 95% (57 cases), while in the control group, the corresponding figure was 2, 8, 20, 10 and 75% (30 cases), comparison between the two groups showed significant difference (χ 2=20 85, P<0 01). The manifestation of symptoms of patients in both groups improved obviously, the pain in loin and back alleviated, spinal motion (flexion forward, extension backward and lateral inclination) improved and thoracic expansion increased. Laboratory indices such as ESR, C 3, IgA and CRP reduced obviously after treatment (P<0 01 or P<0 05), and better effect was shown in the treated group (P<0 05). X ray film after treatment showed improvement in 11 cases in the treated group and 4 in the control group, inter group comparison showed significant difference (χ 2=7.99, P<0 01), the effect of HZJD was better than that of the control. Conclusion: HZJD has definite therapeutic effect in treating AS.

关 键 词：化痰逐瘀解毒汤 治疗 强直性脊柱炎 临床观察 中医药疗法 

分 类 号：R259.9[医药卫生—中西医结合]