痛经宝与复方当归液治疗输卵管阻塞临床与实验研究  

Experimental and Clinical Study of Tong Jing Bao and Angelicae Complex Injection in Treating Fallopian Tube Obstruction

作　　者：连方 孙宁铨 夏桂成[1] 申冬珠 傅友丰 

机构地区：[1]南京中医学院

出　　处：《中西医结合杂志》1991年第5期282-285,262,共4页

摘　　要：48例输卵管阻塞患者随机分为痛经宝加复方当归液治疗组30例,用庆大霉素加生理盐水通管对照组18例。疗程3～6个月。有效率分别为94.6%和56.6%(P<0.01)。妊娠率分别为46.7%和27.8%。实验用雌性家兔22只,以255苯酚胶浆剂复制输卵管炎性阻塞模型。其中8只口服痛经宝加复方当归液通管,7只单用复方当归液通管,另7只生理盐水通管作为对照。结果显示:对于疏通管腔、抗炎、抑制纤维结缔组织增生和促进上皮组织再生,两药并用疗效优于单用复方当归液通管(P<0.05),后者又优于生理盐水通管(P<0.05)。Twenty-two female rabbits with fallopian tube obstruction as the model,were made by 25% Phenol-Tragacanth Mucilage in the laboratory study.Eight rabbits were treated by taking Tong Jing Bao and giving transcervical intrauterine injecting of Angelicae complex injection.Seven were treated with the latter and other seven with 0.9% saline only as the control group.The study showed that in the opening fallopian tube,anti-inflammation,limiting the hyperplasia of fibro-connective tissue and improving the regeneration of epithelial tissue,the first group was more effective than the other two groups(P<0.05).Forty-eight infertile women,in whom the fallopian tube obstruction were proved by hystersalpingography,were divided into two groups for the clinical study.Thirty patients were treated as same as the first group of rabbits.As the control group,other eighteen women were treated with transcervical intrauterine injecting of gentamycin and 0.9% saline in 3 to 6 months.The effective rates were 94.6% and 56.6%(P<0.01)and the subsequent pregnancy rates were 46.7% and 27.8% respectively in the different two groups.

关 键 词：痛经宝 当归注射液 输卵管阻塞 

分 类 号：R711.760.5[医药卫生—妇产科学]