老年阳虚患者超氧化物歧化酶与血清锌铜关系的初步研究  

Study on Superoxide Dismutases and Serum Zn,Cu:Changes in Senile Patients with Yang Deficiency

作　　者：刘福春[1] 吴德林[2] 张加英 周松华[1] 翟美芙[1] 

机构地区：[1]第二军医大学长海医院,上海200433 [2]第二军医大学防护教研室

出　　处：《中西医结合杂志》1991年第8期473-474,共2页

摘　　要：本实验测定了40例老年阳虚患者超氧化物歧化酶含锌铜离子(SOD_(-1))和血清 Zn、Cu,其结果分别为994±125ng/mgHb;63.6±12.1、72.6±10.7μg%。均显著低于正常对照组和老年对照组(P<0.01),血清 Zn 与 SOD_(-1)呈正相关(r=0.34)。文中联系 SOD_(-1)与血清 Zn、Cu 在衰老中的作用,特别是金属离子 Zn、Cu 与 SOD_(-1)之间的关系,对老年阳虚证的发生机理做了初步探讨。This article reports on the respective determinations,which employ RIA and AAS,of superoxide dismutases(SOD-I)and serum Zn,Cu from 40 cases of senile patients with Yang deficiency.The results,which 994±125 ng/mg Hb,63.6±12.1 μg%, 72.6±10.7μg% respectively,were all significantly lower than the normal subjects and senile subjects(P<0.01),and showed that serum Zn was positively interrelated with SOD-I(r=0.34).Integrating SOD-I and the function of serum Zn,Cu in senile especially the relations between Zn, Cu and SOD-I,the authors have made a preliminary probe into the mechanism of senile Yang deficiency's occurrence.

关 键 词：阳虚 超氧物歧化酶 锌 铜 

分 类 号：R255.5[医药卫生—中医内科学]