大隆中毒病人血凝指标的动态分析  

Detection and Analysis of PT,APTT in 93 Talon Poisoning Patients

作　　者：李力[1] 张珂[1] 雷迅 李先梅[1] 

机构地区：[1]四川省肿瘤医院检验科,四川成都610041 [2]四川省成都市金牛区妇幼保健院,四川成都610081

出　　处：《华西医学》2002年第3期368-369,共2页West China Medical Journal

摘　　要：目的 :了解大隆中毒病人诊治过程中各血凝指标的动态变化。方法 :涡流式密度测量原理检测凝血酶原时间 (PT)、活化部份凝血活酶时间 (APTT)。结果 :与正常对照组比较 ,初入院时检查结果PT延长 ,两者差异有极显著性意义 (P <0 0 1) ,APTT延长 (P <0 0 5 )。治疗 2～ 3天后 ,PT、APTT较初入院结果显著缩短 (P <0 0 5 )。临出院前三次检查PT、APTT均恢复到正常水平。APTT异常率较低 ,PT异常率较高 (93 5 % )。PT与APTT变化呈显著正相关 (P <0 0 1)。结论 :大隆中毒病人APTT延长 ,PT显著延长 ,是更敏感的指标。检测PT。Objective:To search the changes in prothrombin time(PT)and activated partial thromboplastin time(APTT)for the Talon poisoning patients.Methods:PT,APTT were measured with trubodensitometry.Results:The results showed that PT,APTT were extended in non-treatment patients as compared with the healthy controls.PT,APTT in the patients treated for 2～3 days were significantly shorter than non-treatment patients(P<0.05).Three continuous detection before the patients should leave hospital found that PT,APTT in the patients treated for three weeks had shortened to healthy controls.The positive rate of PT was 93.5% in Talon poisoning patients.A singnificant positive correction was noted between PT and PPTT(P<0.01).Conclusions:APTT may extend in the Talon poisoning patients.PT extend significantly and it is more sensitive than APTT.The detection of PT,APTT may provide some important information for diagnosis of Talon poisoning and judgment of curative effect.

关 键 词：大隆中毒 凝血酶原时间 活化部分凝血活酶时间 

分 类 号：R595.4[医药卫生—内科学] R991[医药卫生—临床医学]