心理社会应激与疾病关系的病例对照研究  

A CASE-CONTROL STUDY ON PSYCHOSOCIAL STRESS AND DISEASES.

作　　者：栾荣生[1] 薛朝润[2] 李佳圆[1] 张游[2] 阳定宇 罗小辉 高家彦[2] 奚祖庆[4] 郭兰婷[5] 王一平[5] 邓莉[1] 成荫 

机构地区：[1]华西医科大学流行病学教研室,成都610041 [2]四川省医科院附属医院 [3]简阳市卫生防疫站 [4]四川空气分离设备厂医院 [5]华西医科大学附一院

出　　处：《现代预防医学》2000年第3期280-282,共3页Modern Preventive Medicine

基　　金：卫生部科学研究基金!(96- 1- 2 43)

摘　　要：研究生活事件、社会支持以及一般社会经济人口学特征等心理社会应激因素在病例组和对照组的暴露情况 ,探索一般疾病的危险因素。序贯收集四川医科院附属医院 (简阳市 ) 4 11名住院及门诊就医者组成病例组 ,筛选整群抽样的简阳市四川空分厂 6 2 7名无病患职工组成对照组 ,调查其社会经济和人口学特征 ,并以相关量表测量其心理社会应激因素 ,进行 logistic回归分析。结果显示 :负性生活事件、年龄、婚姻状态不良与疾病呈正关联 ,社会支持利用与疾病呈负关联 ,OR分别为 2 .16、 1.2 3、 1.90、 0 .49。因此 ,负性生活事件是疾病的一个重要危险因素 。Objective:To study the relationship between disease states and such factors as socioeconomic and demographic characteristics,life events and social supports.Methods:411 patients in a hospital as the case group and 627 healthy workers in a factory as the control group,both of them in Jiangyang city,were investigated by the life events scale,social supports scale.Results:The logistic regression analysis showed that negative life events,age,worse marital states are positively correlated with diseases and odds ratios(OR) respectively are 2 16,1 23 and 1 90 While social support utilizing is negatively correlated with diseases and OR is 0 49.Conclusion:Negative life events are the important risk factors,and social support utilizing is a major buffering factor for the occurrence of diseases.

关 键 词：病例对照研究 生活事件 社会支持利用 LOGISTIC回归 

分 类 号：R181.23[医药卫生—流行病学]