旋毛虫成虫可溶性抗原免疫小鼠T淋巴细胞亚群的动态变化  

Dynamic changes of T lymphocytes subsets in Trichinella spiralisAWAg immune mice

作　　者：申丽洁 罗志勇[1] 朱声华[2] 

机构地区：[1]大理医学院寄生虫学教研室,云南671000 [2]大理医学院临床医学系

出　　处：《中国人兽共患病杂志》2002年第5期78-80,共3页Chinese Journal of Zoonoses

摘　　要：目的　观察旋毛虫成虫可溶性抗原免疫小鼠T淋巴细胞亚群的动态变化。方法采用流式细胞术分别检测旋毛虫感染后 7、14、2 1、2 8、35天小鼠外周血CD+ 4 、CD+ 8T淋巴细胞的百分率。结果　免疫小鼠CD+ 4 、CD+ 8细胞增加 ,CD+ 4 /CD+ 8细胞比值与正常组比较无明显差异。Objective To observe dynamic changes of T lymphocyte subsets in Trichinella spiralis adult worm soluble antigens (AWAg) immune mice Methods The percentage of CD + 4 and CD + 8 T cells were examined by flow cyteometry on 7,14,21,28,35 days after mice infected with Trichinella spiralis respectively Results CD + 4 and CD + 8 T cells of immune mice increased,the ratio of CD + 4/CD + 8 cells was no difference comparing with normal mice Conclusions The immune function of AWAg immune mice was no inhibited

关 键 词：旋毛虫 抗原 CD4^+细胞 CD8^+细胞 流式细胞术 免疫学 旋毛虫病 动物实验 

分 类 号：R532.14[医药卫生—内科学]