脑室周围白质软化早产儿的闪光视觉诱发电位的发展变化过程  

The evolutionary change of flash visual evoked potentials in preterm infants with periventricular leukomalacia

作　　者：Kato T. Okumura A. Hayakawa F. 江山 

机构地区：[1]Department of Pediatrics, Nagoya University, Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi466-8550, Japan

出　　处：《世界核心医学期刊文摘（神经病学分册）》2005年第7期17-17,共1页Digest of the World Core Medical Journals:Clinical Neurology

摘　　要：Objective: The aim of this study was to prospectively investigate flash visual evoked potential (VEP) findings and their chronological changes in preterm infa nts with cystic periventricular leukomalacia (PVL) during the early neonatal per iod.Methods: The subjects of this study were 14 preterm infants with cystic PVL. The patients underwent serial cranial ultrasonography and diagnosed as having c ystic PVL. Flash VEPs were diagnosed at least twice within the first 3 weeks of life.Results: All infants had at least one or more flash VEP abnormalities.The m ost common finding was ‘absent VEP’, which was seen in 13 infants (93%). ‘De layed latency’was seen in two infants and ‘abnormal waveform’was seen in one infant.Concerning the chronological changes, all records were abnormal in 4 infa nts, and the other 10 had transient normal VEP findings. Among them, flash VEPs changed from normal to abnormal within 10 days after birth in most cases. Conclu sions:Almost all infants with cystic PVL had abnormal flash VEPs within the firs t 3 weeks of life, but chronological changes of flash VEP findings were seen dur ing the period. Significance:This manuscript may be useful as a reference to the flash VEP sin preterm infants with cystic PVL.Objective: The aim of this study was to prospectively investigate flash visual evoked potential (VEP) findings and their chronological changes in preterm infa nts with cystic periventricular leukomalacia (PVL) during the early neonatal per iod.Methods: The subjects of this study were 14 preterm infants with cystic PVL. The patients underwent serial cranial ultrasonography and diagnosed as having c ystic PVL. Flash VEPs were diagnosed at least twice within the first 3 weeks of life.Results: All infants had at least one or more flash VEP abnormalities.The m ost common finding was ‘absent VEP’, which was seen in 13 infants (93%). ‘De layed latency’was seen in two infants and ‘abnormal waveform’was seen in one infant.Concerning the chronological changes, all records were abnormal in 4 infa nts, and the other 10 had transient normal VEP findings. Among them, flash VEPs changed from normal to abnormal within 10 days after birth in most cases. Conclu sions:Almost all infants with cystic PVL had abnormal flash VEPs within the firs t 3 weeks of life, but chronological changes of flash VEP findings were seen dur ing the period. Significance:This manuscript may be useful as a reference to the flash VEP sin preterm infants with cystic PVL.

关 键 词：脑超声波检查 新生儿期 发展变化过程 出生后 neonatal EVOKED twice abnormal CRANIAL BIRTH 

分 类 号：R722.6[医药卫生—儿科]