多核细胞血管组织细胞瘤(法国)  

Multinucleate cells angiohistiocytoma (Fren)

作　　者：Leclerc S Clerici T Rybojad M M.-D. Vignon-Pennamen 刘安 

机构地区：[1]Serviced'Anatomie Pathologique, H.opital Saint Louis, 1, avenue Claude Vellefaux, 75010 Paris, France

出　　处：《世界核心医学期刊文摘（皮肤病学分册）》2005年第10期18-18,共1页Digest of the World Core Medical JOurnals:Dermatology

摘　　要：Introduction. Multinucleate cell angiohistiocytoma is a rare entity. We report two unusual cases of this lesion. Case report. A 39 year-old man had presented since two years an arciform papular eruption of the forehead. A 40 year-old woman had a disseminated maculo-papular eruption since three years. Histological examination of skin samples of the two patients showed a dermal small vessel proliferation, associated with multinucleate cells, and confirmed the diagnosis of multinucleate cell angiohistiocytoma. Discussion. Our cases, typical histologically, have unusual clinical presentation (first case observed in a man, and the second in a disseminated form). Multinucleate cell angiohistiocytoma is a rare benign vascular proliferation individualized in 1985. Clinically, the lesion consists in small circumscribed papules. Acral sites and notably of the dorsum of the hands are the more frequent topography. It generally occurs in women aged over 50 years. Histologically, there is a dermal proliferation of capillaries and venules,and a fibrosis associated with the interstitial mononucleate cells and multinucleate cells.Introduction. Multinucleate cell angiohistiocytoma is a rare entity. We report two unusual cases of this lesion. Case report. A 39 year-old man had presented since two years an arciform papular eruption of the forehead. A 40 year-old woman had a disseminated maculo-papular eruption since three years. Histological examination of skin samples of the two patients showed a dermal small vessel proliferation, associated with multinucleate cells, and confirmed the diagnosis of multinucleate cell angiohistiocytoma. Discussion. Our cases, typical histologically, have unusual clinical presentation (first case observed in a man, and the second in a disseminated form). Multinucleate cell angiohistiocytoma is a rare benign vascular proliferation individualized in 1985. Clinically, the lesion consists in small circumscribed papules. Acral sites and notably of the dorsum of the hands are the more frequent topography. It generally occurs in women aged over 50 years. Histologically, there is a dermal proliferation of capillaries and venules,and a fibrosis associated with the interstitial mononucleate cells and multinucleate cells.

关 键 词：组织细胞瘤 多核细胞 组织学检查 罕见病例 肢体末端 限局性 种皮 

分 类 号：R751[医药卫生—皮肤病学与性病学]