用Xecl准分子激光治疗特应性皮炎  

Treatment of atopic dermatitis with the xenon chloride excimer laser

作　　者：Baltás E. Csoma Z. Bodai L. 任建文 

机构地区：[1]Department of Dermatology and Allergology,University of Szeged,POBox 427,H-6701 Szeged,Hungary

出　　处：《世界核心医学期刊文摘（皮肤病学分册）》2006年第10期6-6,共1页Digest of the World Core Medical JOurnals:Dermatology

摘　　要：Background:Narrow-band ultraviolet B phototherapy is an effictive and safe treatment for atopic dermatitis.We have previously found that the 308 nm xenon chloride excimer laser was more effective than the narrow-band ultraviolet B light for the treatment of psoriasis,suggesting that ultraviolet B laser might offer advantages over narrow-band ultraviolet B.Objective:The purpose of this study was to evaluate the therapeutic efficacy of the 308 nm excimer laser in atopic dermatitis.Patients and methods:Fifteen patients with atopic dermatitis(less than 20%body area involvement)were treated with a xenon chloride excimer laser(XTRAC laser,Photomedex Inc.)twice weekly.The severity of the atopic dermatitis was assessed via(i)a clinical score characterizing the intensity of erythema,infiltration,lichenification and excoriation;(ii)the quality of life,determined by means of a questionnaire;and(iii)a visual linear analogue scale,with which the patients scored the severity of their pruritus.Results:After 1 month of laser therapy,the clinical scores were significantly lower than the initial values.Similar decreases were observed for the quality of life and pruritus scores.No serious or unpleasant side-effects were observed.Conclusion:These results suggest that thexenon chloride excimer laser is an effective and well-tolerated treatment for localized atopic dermatitis.Background:Narrow-band ultraviolet B phototherapy is an effictive and safe treatment for atopic dermatitis.We have previously found that the 308 nm xenon chloride excimer laser was more effective than the narrow-band ultraviolet B light for the treatment of psoriasis,suggesting that ultraviolet B laser might offer advantages over narrow-band ultraviolet B.Objective:The purpose of this study was to evaluate the therapeutic efficacy of the 308 nm excimer laser in atopic dermatitis.Patients and methods:Fifteen patients with atopic dermatitis(less than 20%body area involvement)were treated with a xenon chloride excimer laser(XTRAC laser,Photomedex Inc.)twice weekly.The severity of the atopic dermatitis was assessed via(i)a clinical score characterizing the intensity of erythema,infiltration,lichenification and excoriation;(ii)the quality of life,determined by means of a questionnaire;and(iii)a visual linear analogue scale,with which the patients scored the severity of their pruritus.Results:After 1 month of laser therapy,the clinical scores were significantly lower than the initial values.Similar decreases were observed for the quality of life and pruritus scores.No serious or unpleasant side-effects were observed.Conclusion:These results suggest that thexenon chloride excimer laser is an effective and well-tolerated treatment for localized atopic dermatitis.

关 键 词：特应性皮炎 XECL 准分子激光 激光仪 银屑病 瘙痒程度 中波紫外线 表皮剥脱 皮损面积 临床评分 

分 类 号：R758.2[医药卫生—皮肤病学与性病学]