普鲁卡因酰胺的有用性对心律失常的电生理危险分层提出了挑战  

Usefulness of procainamide challenge for electrophysiologic arrhythmia risk stratification

作　　者：Schreibman D. S. McPherson C. A. Rosenfeld L. E. 王永兴 

出　　处：《世界核心医学期刊文摘（心脏病学分册）》2005年第4期32-33,共2页

摘　　要：Among 58 consecutive patients who underwent electrophysiologic testing for ris k assessment and who subsequently received a third-generation implantable cardi overter-defibrillator, 39 had ventricular tachycardia induced in the baseline s tate and 19 had ventricular tachycardia induced only after administration of int ravenous procainamide, increasing the yield of electrophysiologic risk assessmen t by 49%. At follow-up, ventricular arrhythmias requiring implantable cardiove rter-defibrillator termination occurred in 14 of 39 patients inducible in the b aseline state and in 7 of 19 patients inducible only with intravenous procainami de. The provocative use of intravenous procainamide during electrophysiologic ri sk assessment increases the detection rate for risk of sustained ventricular arr hythmias with no loss of positive predictive value.Among 58 consecutive patients who underwent electrophysiologic testing for ris k assessment and who subsequently received a third-generation implantable cardi overter-defibrillator, 39 had ventricular tachycardia induced in the baseline s tate and 19 had ventricular tachycardia induced only after administration of int ravenous procainamide, increasing the yield of electrophysiologic risk assessmen t by 49%. At follow-up, ventricular arrhythmias requiring implantable cardiove rter-defibrillator termination occurred in 14 of 39 patients inducible in the b aseline state and in 7 of 19 patients inducible only with intravenous procainami de. The provocative use of intravenous procainamide during electrophysiologic ri sk assessment increases the detection rate for risk of sustained ventricular arr hythmias with no loss of positive predictive value.

关 键 词：普鲁卡因酰胺 电生理检查 危险分层 危险评估 阳性预测值 植入式 第三代 

分 类 号：R541.7[医药卫生—心血管疾病]