ST段异常和早搏是新发房颤的预测因素:Niigata预防医学研究  

ST-segment abnormalities and premature complexes are predictors of new-onset atrial fibrillation: The Niigata Preventive Medicine Study

作　　者：Watanabe H. Tanabe N. Makiyama Y. 朱冰坡 

机构地区：[1]Dr.Division of Clinical Pharmacology, Vanderbilt University School of Medicine, Nashville, TN, United States

出　　处：《世界核心医学期刊文摘（心脏病学分册）》2007年第3期20-20,共1页

摘　　要：背景:已知左心室肥厚是房颤(AF)的危险因素。然而,目前尚不知道是否还有其他的心电图异常与AF的发生有关。方法:这是一项基于社区的队列研究,资料来自一个年度体检数据库。Background: Left ventricular hypertrophy is a known risk factor for atrial fibrillation(AF). However, it is not well understood whether other electrocardiogram abnormalities are associated with development of AF. Methods: This was a community-based cohort study based upon a database of annual health examinations. We included 63,386 subjects aged ≥50 years, without baseline AF(including atrial flutter), structural heart disease, or heart failure, who completed the annual examination during a 10-year follow-up period(1991-2002). The electrocardiographic risk factors for AF were studied in the subjects. Results: Atrial fibrillation developed in 873 subjects. Age, male sex, body mass index, hypertension, systolic and diastolic blood pressure, and diabetes were significant risk factors for the development of AF. In multivariable logistic regression analysis adjusted for these risk factors, electrocardiographic left ventricular hypertrophy(odds ratio[OR], 1.43), ST-segment abnormality without left ventricular hypertrophy(OR, 1.89), and the presence of premature complexes during a 10-second recording(OR, 2.89) were significantly associated with AF, whereas either right(OR, 0.84) or left bundle branch block(OR, 0.96) was unrelated. The risk for AF increased progressively with the severity of both ST-segment change and premature complexes. Conclusions: ST-segment abnormality and comparably high-frequency premature complexes were each associated with increased risk for the development of AF. These electrocardiographic findings may be useful to stratify high-risk subjects for new-onset AF.

关 键 词：Niigata ST段异常 心室肥厚 心电图异常 体检数据 队列研究 左束支传导阻滞 房扑 右束支 

分 类 号：R541.75[医药卫生—心血管疾病]