创口净抗菌作用的体外研究  被引量：2

Study on inhibition of Chuang Kou Jing against bacteria in vitro</em> <p class='article-op'> <span id="bdshare" class="bdshare_t bds_tools get-codes-bdshare baidufx"><span><span class="bds_more" style="display: block; width: 62px; height: 29px; background: url(/images/share.gif) no-repeat!important; padding: 0;"></span></span></span> </p> <p class="article-source"> <a href ='/article/read.aspx?id=6837797' class='btnTitle btnIsView' target='_blank'><img alt='在线阅读' src='/images/btn-read.png'/></a><a class='btnTitle btnIsView' href="javascript:showdown('fOIHOaefCTxfzw1bzRwSG4bbsH3TWL3ddK09Rp3tlac=')"><img alt="下载全文" src="/images/btn-down.png" /></a> <input id="hiddowninfo" type="hidden" value="fOIHOaefCTxfzw1bzRwSG4bbsH3TWL3ddK09Rp3tlac="/> </p> <div class="collect" style="display: none"> <h5>我的收藏</h5> <div class="cnt"> <p> 名 称：<input type="text" name="collTitle" id="collSumTitle" /> </p> <p> 注 释：<input type="text" name="collRemark" id="collSumRemark" /> </p> <p style="text-align: 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target='_blank' ><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=A%3d%5b%e5%bc%a0%e5%ad%a6%e5%bf%8d%5d' title='张学忍[3]'>张学忍[3]</a> <a href='/writer/article.aspx?id=100000004472052' target='_blank' ><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=A%3d%5b%e4%bc%8d%e5%bf%a0%e8%af%9a%5d' title='伍忠诚[3]'>伍忠诚[3]</a> <em> </em></p><p class='organ'><strong>机构地区：</strong><a href='/organ/article.aspx?id=63832&subid=&showname=&searchtype=' target='_blank'><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=S%3d%e7%ac%ac%e5%9b%9b%e5%86%9b%e5%8c%bb%e5%a4%a7%e5%ad%a6%e5%94%90%e9%83%bd%e5%8c%bb%e9%99%a2%e6%84%9f%e6%9f%93%e7%97%85%e4%b8%ad%e5%bf%83' title='[1]第四军医大学唐都医院感染病中心,陕西西安710038'>[1]第四军医大学唐都医院感染病中心,陕西西安710038</a> <a href='/organ/article.aspx?id=63832&subid=&showname=&searchtype=' target='_blank'><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=S%3d%e7%ac%ac%e5%9b%9b%e5%86%9b%e5%8c%bb%e5%a4%a7%e5%ad%a6%e5%94%90%e9%83%bd%e5%8c%bb%e9%99%a2%e5%91%bc%e5%90%b8%e5%86%85%e7%a7%91' title='[2]第四军医大学唐都医院呼吸内科,陕西西安710038'>[2]第四军医大学唐都医院呼吸内科,陕西西安710038</a> <a href='/organ/article.aspx?id=2705&subid=&showname=&searchtype=' target='_blank'><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=S%3d%e5%85%b0%e5%b7%9e%e5%86%9b%e5%8c%ba%e6%80%bb%e5%8c%bb%e9%99%a2%e5%ae%9e%e9%aa%8c%e7%a7%91' title='[3]兰州军区总医院实验科,甘肃兰州730050'>[3]兰州军区总医院实验科,甘肃兰州730050</a> <em> </em></p><p class='from'><strong>出　　处：</strong><a href='/journal/summary.aspx?gch=91335X' target='_blank'><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=J%3d%5b%e8%a5%bf%e5%8c%97%e5%9b%bd%e9%98%b2%e5%8c%bb%e5%ad%a6%e6%9d%82%e5%bf%97%5d' title='西北国防医学杂志'>《西北国防医学杂志》</a>2002年第5期337-339,共3页<em>Medical Journal of National Defending Forces in Northwest China</em></p><p class='fund'><strong>基　　金：</strong>.NULL.</p><p class='abstrack'><strong>摘　　要：</strong>目的:了解创口净对常见菌的抗菌作用。方法:测定创口净在体外破伤风梭菌、产气夹膜梭菌,绿脓杆菌、金黄色葡萄球菌、大肠杆菌的抑菌试验,并与常用消毒剂比较分析。结果:创口净对破伤风梭菌和产气夹膜梭菌的最小抑菌浓度与大肠杆菌均为1.6μg·ml-1,对金黄色葡萄球菌的最小抑菌浓度为0.78μg·ml-1,而绿脓杆菌为12.5μg·ml-1;创口净在2.5min就能杀灭绝大多数细菌,而75%乙醇、0.1%新洁尔灭、0.05%洗必泰所需时间更长。结论:创口净可有效地杀灭常见致病性厌氧菌和非厌氧菌,为一种高效、快速的广谱抗菌剂,可用于各种创伤感染的预防和治疗。<em><Abstrcat>Objective:To investigate the inhibition of Chuang Kou Jing (CKJ)against general infectious bacteria.Methods:To analyse the inhibition of CKJ against the bacteria such as Clostridium perfringens, Clostridiumtetani,Staphyloccus aureus, Escherichia coli in vitro and compared with other disinfections.Results:The minimal inhibitory concentration (MIC) of CKJ for C. Perfringens, C. tetani and E. Coli were all 1.6 μg·ml-1. The MIC for S. aureus and P. Auruginosa were 0.78 μg·ml-1 and 12.5 μg·ml-1 respectively. It took 2.5 min for CKJ to kill most of the bacteria, but it took more time for 75% alcohol, 0.1 % bromogeramine, and 0.05% Chlohexidine.Conclusion:CKJ can efficiently inhibit or kill the general anaerobic and aerobic bacteria, it is a high effective, speed antibacterial agent, and can be used to treat and prevent various traumatic wound infection.</em></p><p class='subject'><strong>关 键 词：</strong><a href='/subject/article.aspx?id=9178018' target='_blank'><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=K%3d%5b%e5%88%9b%e5%8f%a3%e5%87%80%5d' title='创口净'>创口净</a> <a href='/subject/article.aspx?id=5187539' target='_blank'><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=K%3d%5b%e6%8a%97%e8%8f%8c%e4%bd%9c%e7%94%a8%5d' title='抗菌作用'>抗菌作用</a> <a href='/subject/article.aspx?id=2573520' target='_blank'><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=K%3d%5b%e4%bd%93%e5%a4%96%e7%a0%94%e7%a9%b6%5d' title='体外研究'>体外研究</a> <a href='/subject/article.aspx?id=830100' target='_blank'><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=K%3d%5b%e5%8e%8c%e6%b0%a7%e8%8f%8c%5d' title='厌氧菌'>厌氧菌</a> <a href='/zk/search.aspx?key=K%3d%5b%e9%9d%9e%e5%8e%8c%e6%b0%a7%e8%8f%8c%5d' title='非厌氧菌'>非厌氧菌</a> <a href='/subject/article.aspx?id=3781582' target='_blank'><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=K%3d%5b%e5%a4%96%e7%94%a8%e8%8d%af%5d' title='外用药'>外用药</a> </p><p class='class'><strong>分 类 号：</strong><a href='/zk/search.aspx?key=C%3dR965' title='R965'>R965</a>[<a href = '/domain/article.aspx?id=514' >医药卫生—药理学</a>] </p> </div> <div id="content_wzxg" name="wzxg" class="article-graph"> <object width="695" height="250" classid="clsid:D27CDB6E-AE6D-11cf-96B8-444553540000" id="FlashID"> <param value="../flash/relation.swf" name="movie"> <param value="high" name="quality"> <param value="opaque" name="wmode"> <param value="6.0.65.0" name="swfversion"> <param 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