两种不同方法测定复方环丙沙星栓中两组分含量的比较  被引量：1

Comparison of dualwavelength Kratio and linear regression UVspectrophotometry of compound ciprofloxacin suppositories</em> <p class='article-op'> <span id="bdshare" class="bdshare_t bds_tools get-codes-bdshare baidufx"><span><span class="bds_more" style="display: block; width: 62px; height: 29px; background: url(/images/share.gif) no-repeat!important; padding: 0;"></span></span></span> </p> <p class="article-source"> <a href ='/article/read.aspx?id=6837857' class='btnTitle btnIsView' target='_blank'><img alt='在线阅读' src='/images/btn-read.png'/></a><a class='btnTitle btnIsView' href="javascript:showdown('MgdFDkiTxz7uxFlDrCL4JYRRhER7Q4B5LjPK07NbHr8=')"><img alt="下载全文" src="/images/btn-down.png" /></a> <input id="hiddowninfo" type="hidden" value="MgdFDkiTxz7uxFlDrCL4JYRRhER7Q4B5LjPK07NbHr8="/> </p> <div class="collect" style="display: none"> <h5>我的收藏</h5> <div class="cnt"> <p> 名 称：<input type="text" name="collTitle" id="collSumTitle" /> </p> <p> 注 释：<input type="text" name="collRemark" 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title='吴勇杰[1]'>吴勇杰[1]</a> <em> </em></p><p class='organ'><strong>机构地区：</strong><a href='/organ/article.aspx?id=10463&subid=&showname=&searchtype=' target='_blank'><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=S%3d%e5%85%b0%e5%b7%9e%e5%8c%bb%e5%ad%a6%e9%99%a2%e8%8d%af%e5%ad%a6%e7%b3%bb' title='[1]兰州医学院药学系,甘肃兰州730000'>[1]兰州医学院药学系,甘肃兰州730000</a> <a href='/organ/article.aspx?id=2705&subid=&showname=&searchtype=' target='_blank'><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=S%3d%e5%85%b0%e5%b7%9e%e5%86%9b%e5%8c%ba%e5%85%b0%e5%b7%9e%e6%80%bb%e5%8c%bb%e9%99%a2%e8%8d%af%e6%9d%90%e7%a7%91' title='[2]兰州军区兰州总医院药材科,730050'>[2]兰州军区兰州总医院药材科,730050</a> <em> </em></p><p class='from'><strong>出　　处：</strong><a href='/journal/summary.aspx?gch=91335X' target='_blank'><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=J%3d%5b%e8%a5%bf%e5%8c%97%e5%9b%bd%e9%98%b2%e5%8c%bb%e5%ad%a6%e6%9d%82%e5%bf%97%5d' title='西北国防医学杂志'>《西北国防医学杂志》</a>2002年第5期364-366,共3页<em>Medical Journal of National Defending Forces in Northwest China</em></p><p class='fund'><strong>基　　金：</strong>.NULL.</p><p class='abstrack'><strong>摘　　要：</strong>目的:建立测定复方环丙沙星栓的双波长系数倍率法和一元线性回归法。方法:应用两种方法原理,在紫外分光光度上确定最佳波长对和比例系数K值,建立工作曲线。结果:两种方法可对样品不需分离,直接测定环丙沙星和甲硝唑含量,经统计学处理,无显著差异。两种方法测得环丙沙星和甲硝唑含量的平均回收率为:(99.33±0.77)%、(100.63±0.48)%和(98.74±0.82)%、(100.43±0.61)%。结论:两种测定方法可行、简单、快速、准确。<em><Abstrcat>Objective:Compound ciprofloxacin suppositories were determined by dualwavelength Kratio and linear regression UVspectrophotometry.Methods:Wavelength pair and ratio K were determined by the principle and the standard curves were set up.Results:Ciprofloxacin and metronidazole in the suppositories were simultaneously determined without separation.The two methods had no marked difference by statistics,the average recoveries of ciprofloxacin and metronidazole were (99.33±0.77)%, (100.63±0.48)% and (98.74±0.82)%, (100.43±0.61)%,respectively.Conclusion:The two methods are available,simple, rapid and accurate.</em></p><p class='subject'><strong>关 键 词：</strong><a href='/subject/article.aspx?id=6863853' target='_blank'><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=K%3d%5b%e5%a4%8d%e6%96%b9%e7%8e%af%e4%b8%99%e6%b2%99%e6%98%9f%e6%a0%93%5d' title='复方环丙沙星栓'>复方环丙沙星栓</a> <a href='/subject/article.aspx?id=867672' target='_blank'><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=K%3d%5b%e8%8d%af%e5%93%81%e6%a3%80%e9%aa%8c%5d' title='药品检验'>药品检验</a> <a href='/subject/article.aspx?id=4074812' target='_blank'><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=K%3d%5b%e7%b3%bb%e6%95%b0%e5%80%8d%e7%8e%87%e6%b3%95%5d' title='系数倍率法'>系数倍率法</a> <a href='/zk/search.aspx?key=K%3d%5b%e4%b8%80%e5%85%83%e7%ba%bf%e6%80%a7%e5%9b%9e%e5%bd%92%e6%b3%95%5d' title='一元线性回归法'>一元线性回归法</a> <a href='/subject/article.aspx?id=5491370' target='_blank'><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=K%3d%5b%e7%8e%af%e4%b8%99%e6%b2%99%e6%98%9f%5d' title='环丙沙星'>环丙沙星</a> <a href='/subject/article.aspx?id=5814587' target='_blank'><b class='type_ico_id'></b></a><a href='/zk/search.aspx?key=K%3d%5b%e7%94%b2%e7%a1%9d%e5%94%91%5d' title='甲硝唑'>甲硝唑</a> <a href='/zk/search.aspx?key=K%3d%5b%e5%90%ab%e9%87%8f%e6%b5%8b%e5%ae%9a%5d' title='含量测定'>含量测定</a> </p><p class='class'><strong>分 类 号：</strong><a href='/zk/search.aspx?key=C%3dR927.2' title='R927.2'>R927.2</a>[<a href = '/domain/article.aspx?id=509' >医药卫生—药学</a>] </p> </div> <div id="content_wzxg" name="wzxg" class="article-graph"> <object width="695" height="250" classid="clsid:D27CDB6E-AE6D-11cf-96B8-444553540000" id="FlashID"> <param value="../flash/relation.swf" name="movie"> <param value="high" name="quality"> <param value="opaque" name="wmode"> <param value="6.0.65.0" name="swfversion"> <param value="dataUrl=/ajax/articlerelativegraph.ashx?id=6837857" name="flashVars"> <embed width="695" height="250" src="../flash/relation.swf" type="application/x-shockwave-flash" quality="high" wmode="opaque" 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