非离子型低渗造影剂相关性肾损害的临床分析  

Clinical analysis of nonionic contrast media induced nephropathy

作　　者：李占军[1] 周智洋[2] 王颖[1] 邱建平[2] 何志诚[2] 王馨华[2] 

机构地区：[1]广东省珠海市中山大学附属第五医院放射科,519000 [2]广东省广州市中山大学附属第六医院放射科,510655

出　　处：《临床医药实践》2009年第9X期690-692,共3页Proceeding of Clinical Medicine

摘　　要：目的:了解冠脉介入治疗患者造影剂相关性肾病危险因素的发生情况。方法:收集240例接受冠脉介入治疗患者的临床资料,分为合并症组和无合并症组,合并症组又分为高血压组、糖尿病组、和高血压合并糖尿病组,分析检查者的血肌酐变化以及CIN发生的情况。结果:240例患者中,有合并症组出现CIN16例,而无合并症组无一例出现CIN,有合并症组肌酐上升幅度较无合并症组高,两组间差异有统计学意义,同时发生肌酐上升的例数亦较无合并症组高,两组间比较差异有统计学意义;而糖尿病和高血压组两组发生CIN的情况大致相同,糖尿病合并高血压组发生CIN的例数明显高于其他2组。结论:行冠脉介入治疗的患者,存在CIN的危险因素十分普遍,早期给予积极而有效的预防措施十分必要。Objective:To evaluate the risk factor of con-trast media induced nephropathy(CIN) in patients with coronary artery disease(CAD) undergoing coronary interventional therapy.Methods:240 patients with CAD were divided into uncomplicated group and complications group which was divided into complications of hypertension group,diabetes group,diabetes mellitus and hypertension group.Analysis of serum creatinine changes in patients with CIN happened.Results:240 cases of patients,the complications group have 16 cases of patients with CIN,uncomplicated group there was no case of CIN,the complications group creatinine increase were higher than uncomplicated group,the difference between the two groups was significant,simultaneous rise in creatinine number of cases was higher than without complications,compared between the two groups were significantly different;and diabetes and hypertension group,CIN occurred in the case of two groups of roughly the same,diabetes with hypertension in patients with CIN group was significantly higher than the other 2 groups,and There was a significant statistical difference.Conclusion:Coronary intervention in patients treated with the existence of the risk factors of CIN is widespread,early to give a positive and effective preventive measures is necessary.

关 键 词：造影剂相关性肾损害 冠脉介入治疗 非离子造影剂 

分 类 号：R595.3[医药卫生—内科学]