酸性染料法测定盐酸地尔硫及其片剂含量的研究  

Determination of Diltiazem Hydrochloride and Its Tablets by the Acid Dyestuff Method

作　　者：梁桂贤[1] 高山[1] 李梅[1] 

机构地区：[1]山西职工医学院,山西太原030012

出　　处：《山西职工医学院学报》2002年第3期1-2,共2页Journal of Shanxi Medical College for Continuing Education

摘　　要：目的 :根据盐酸地尔硫 艹卓 与溴甲酚绿形成有色离子对的性质 ,建立酸性染料法测定盐酸地尔硫 艹卓 及其片剂的方法。方法 :盐酸地尔硫 艹卓 与溴甲酚绿形成有色离子对络合物用氯仿萃取后比色。结果 :最大吸收波长λmas=(415±1)nm ,A -C回归方程为 :A =0 0 4 37C - 10 3 r=0 9996 (n =3) ,线性范围为 6 μg/ml～ 18μg/ml。结论 :该法灵敏准确 ,专属性强 。Objective The acid dyestuff method for the determination of diltiazem hydrochloride and its tablets was established.Methods The extraction and an UV spectrophotometric method were used.Results λ mas =(415±1)nm, A - C regression equation was A =0 043 7 C -10 3 , r =0 999 6( n =3),the liner range was 6 μg/ml～18 μg/ml.The results agreed with obtained by the C P(1995) method.Conclusion The acid dyestuff method is specific,sensitive,simple and rapid.

关 键 词：盐酸地尔硫ZHUO 酸性染料法 含量测定 心血管系统药物 

分 类 号：R927.2[医药卫生—药学] R972