慢性非细菌性前列腺炎尿流动力学改变及其对α-受体阻断剂的反应  

The Urodymanic Change and Its Reaction to Alpha-blocker in Treatment of Nonbacterial Prostatitis

作　　者：许明[1] 张永康[1] 邹秋锋[1] 

机构地区：[1]复旦大学附属中山医院泌尿外科,上海20003

出　　处：《中国临床医学》2002年第4期371-373,共3页Chinese Journal of Clinical Medicine

摘　　要：目的 :从尿流动力学角度探讨慢性非细菌性前列腺炎的可能病因及治疗选择。方法 :96例门诊诊断为慢性非细菌性前列腺炎患者根据尿流动力学的变化按其最大尿流率大于或小于 15ml/s分成A、B两组 ;接受基本相同的治疗 ,服用哈乐或马沙尼 ,随访 6周 ,每 2周随访一次 ;观察两组尿流率的变化和患者临床症状、症状评分和前列腺液中WBC计数的变化以及两者之间的关系。结果 :A组患者尿流率变化无统计学意义 ;B组患者尿流率治疗前后的变化有统计学意义 ;且两组患者对治疗的反应差异有统计学意义。结论 :对临床表现以梗阻症状为主、尿流率低下的患者使用α -受体阻断剂有一定疗效 ;而对不是以梗阻症状为主 (如表现为尿频等刺激症状 ) ,尿流率基本正常的患者 ,使用α -受体阻断剂应慎重。Objective: To study the urodymanic change and its reaction to α-blocker in treatment of nonbacterial prostatitis(NBP). Methods: 96 outpatients from May 1999 to May 2001 were divided into in two groups accordingly to his peak flow in the urodynamic examination. In A group, the patients peak flow was more than 15 ml/s, in B group the patients peak flow was less than 15ml/s. Allpatients were treated with the same drugs: α-blocker(terazosin or hytrin) ,the treatment period was 6 weeks ,and follow-up were done every two weeks. Results: There was no statistically differences after treatment in A group, presenting similarities in peak flow and mean flow; but there was statistically differences after treatment in B group, presenting obvious changes in peak flow and mean flow. There was statistically differences after treatment in the two groups presenting in the rates the symptomatic relieves,the symptomatic score (SFQ) improvements, and the derease of leucocytes (WBC)counting in EPS (Expressed prostitic secretion). Conclusion: α-blocker can elevate the cure rate of the patients with low peak flow and obstructive symptoms in the treatment of NBP.

关 键 词：尿流动力学 非细菌性前列腺炎 Α-受体 NBP 

分 类 号：R697.33[医药卫生—泌尿科学]