支原体与早产、新生儿肺炎关系研究  

Study on The Relations between Premature、 Pneumonic Neonate and Mycoplasma Infection

作　　者：朱云霞[1] 龚晓红[1] 周勤[1] 

机构地区：[1]江苏省无锡市妇幼保健院,江苏无锡214002

出　　处：《疾病监测》2002年第9期325-327,共3页Disease Surveillance

摘　　要：目的:了解解脲脲原体（Uu）、肺炎支原体（Wpn）、人型支原体（Mh）、生殖支原体（Mg）、发酵支原体（Mf）5种支原体感染与早产、新生儿肺炎的关系。方法:收集151例正常新生儿（剖宫产98例）、105例早产儿（剖宫产50例）和71例新生儿肺炎者（剖宫产48例）出生24小时内的咽拭子标本,应用套式聚合酶链式反应（nestedPolymerase Chain Reaction, nPCR）技术检测5种支原体的特异性核酸。结果:正常新生儿检出Un、Mpn和Mh3种支原体,阳性率分别为8.6％、3.3％和2.0％;早产儿检出Uu、Mpn、Mh和Mg4种支原体,阳性率分别为44.8％、21.9％、10.5％和4.8％,均明显高于正常新生儿（P均<0.01,RR均>3）;新生儿肺炎者检出Uu、Mpn、Mh和Mg4种支原体,其中Uu、Mpn分别为42.3％、25.4％明显高于正常新生儿（P均<0.01,RR均>3）。剖宫产出的早产儿和新生儿肺炎者支原体检出率分别为74.0％和56.3％,明显高于正常新生儿的10.2％（P均<0.01,RR均>3）。结论:Uu、Mpn、Mh和Mg等围产期感染可致早产和新生儿肺炎。To explore the relations between the premature 、 pneumonic neonate and the infections of Ureaplas-ma urealyticum (Uu)、 Mycoplasma pneumoniae ( Mpn)、 M. hominis ( Mh)、M. genitalium ( Mg) and M. fermentans (Mf) . The specimens of the throat swab were obtained in 151 health neonate 、 105 premature and 71 pneumonic neo-nate. These specimens were detected by nested polymerase chain reaction. The results showed that the positive rates of Uu、Mpn and Mh in health neonate were 8.6% 、3.3% and 2.0% ; those of Uu、Mp、Mh and Mg in premature were 44.8%、21.9%、10.% and 4.8% (Pall <0.01, RR all >3.0); those of Uu and Mpn in pneumonic neonate were 42.3% and 25.4% (P all < 0.01, RR all > 3.0). These results indicated that mycoplasma infection might be the important cause of the premature 、 pneumonic neonate.

关 键 词：支原体感染 早产儿 新生儿肺炎 

分 类 号：R722.135[医药卫生—儿科]