150例喹诺酮类药物不良反应分析  

Adverse reactions to goinolones: Analysis of 150 case reports

作　　者：李罄[1] 冷金华[1] 

机构地区：[1]广州军区武汉总医院,湖北武汉430070

出　　处：《药物不良反应杂志》2002年第4期221-223,共3页Adverse Drug Reactions Journal

摘　　要：目的:了解喹诺酮类药物在临床治疗中发生的不良反应情况,警惕该类药物的不良反应发生。方法:对我院 ADR监测中心收到的喹诺酮类药物 ADR报表进行整理和分析。结果:150例 ADR报表中涉及 9种喹诺酮类药物,主要不良反应表现为皮疹、静脉炎和消化系统症状,其次为心血管系统、神经系统等多种症状。结论:喹诺酮类药物引起的不良反应症状多,严重者可危及生命。只要及时停药并对症治疗,不良反应症状可逆转。Objective: To determine ADR occurrence associated with quinolones in clinical practices. Method: ADR reports received by the monitoring center in our hospital were processed and analysed. Results: Nine drugs of quinolones were involved in 150 ADR case reports. The ADR manifestations mainly covered rash, phlebitis, and troubles in alimentary system, cardiovascular system and nervous system. Conclusion: Quinolones can cause unwanted reactions, even serious ones. The solution for the problem is the withdrawal of drug and the use of expectant treatment.

关 键 词：喹诺酮类药物 不良反应 抗菌药物 

分 类 号：R978[医药卫生—药品]