大白鼠减压缺氧性肺水肿的形态计量研究  

Morphometric study on pulmonary edema induced by hypobaric hypoxia in rats

作　　者：徐登云[1] 王之贤[1] 弓景波[1] 于涛 张国春 

机构地区：[1]军事医学科学院卫生学环境医学研究所

出　　处：《中国体视学与图像分析》1997年第1期16-21,共6页Chinese Journal of Stereology and Image Analysis

摘　　要：实验采用形态计量方法探讨大白鼠模拟６ｋｍ减压缺氧、４、８和１２ｈ条件下间质性肺水肿（ＩＰＥ）和冷水游泳负荷后８ｋｍ减压缺氧３－６ｈ肺泡性肺水肿（ＡＰＥ）的发生情况。结果表明，６ｋｍ减压缺氧各组，肺细支气管动脉周围腔明显扩大，冷负荷后缺氧肺水肿的面积较单纯８ｋｍ减压缺氧组和单纯冷负荷后缺氧组有显著性差别。The development of IPE was observed with the morphometric methods in 40 male rats under simulated hypoxia at height of 6km for 4h, 8h and 12h. The development of APE was observed in 50 male rats under simulated hypoxia at height of 8km after swimming load in cool water. The results showed that the surrounding spaces of bronchial arteries were obviously extended under the simulating hypoxic condition in the 6km groups when compared with control group. The area of the APE and its Vv were apparently enlar ged under simulated hypoxic condition in the 8km group after swimming load in cool water, when compared with the groups of only 8km hypoxia or only swimming load in cool water.

关 键 词：形态计量 减压缺氧 间质性肺水肿 肺泡性肺水肿 

分 类 号：R541.63[医药卫生—心血管疾病]