聚乳酸管注入白芨胶和雪旺细胞修复周围神经缺损的实验研究  

Repair of Peripheral Nerve Defect Using Polylactic Acid Conduit withBletilla Colloid and Schwann Cells

作　　者：刘俊宾[1] 夏仁云[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院骨科,湖北武汉430030

出　　处：《汕头大学医学院学报》2002年第3期149-151,F004,共4页Journal of Shantou University Medical College

摘　　要：目的 :研究聚乳酸管注入白芨胶和雪旺细胞对周围神经再生的影响。方法 :30只Wister大鼠分为两组 ,分别在聚乳酸管 (A组 )注入或不注入 (B组 )白芨胶和雪旺细胞来桥接单侧坐骨神经 10mm缺损。术后第 8、 12周进行显微解剖学、组织学等检查。结果 :A组神经再生明显。结论Objective:To study the influence of peripheral nerve regeneration through polylactic acid conduit with bletilla colloid(BC)and schwann cells(SCs).Methods:Thirty Wister rats were randomly divided into two groups.The polylactic acid conduit with(Group A)or without(Group B)BC and SCs bridged single lateral sciatic nerve defect 10 millimetres in length in rats.At 8th,12th week after operated,the histological method and microdissective technique were carried out.Results:Group A could accelerate peripheral nerve regeneration efficiently.Conclusion:BC carried SCs in polylactic acid conduit can accelerate and increase perpheral nerve regeneration.

关 键 词：聚乳酸管 神经再生 雪旺细胞 白芨胶 周围神经缺损 

分 类 号：R651.3[医药卫生—外科学]