罗哌卡因与利布混合液在臂丛麻醉中比较研究  

Comparative study of ropivacaine with lidocaine-bupivacaine in brachial plexus block

作　　者：徐志荣[1] 李元海[1] 李磊[1] 戴秀萍[1] 

机构地区：[1]安徽医科大学第一附属医院麻醉科,合肥230032

出　　处：《安徽医药》2002年第3期16-17,共2页Anhui Medical and Pharmaceutical Journal

摘　　要：目的　研究罗哌卡因在臂丛麻醉中的临床应用效果。方法　选择 40例行上肢手术的病人 ,随机分两组 ,每组 2 0例。RP组 :罗哌卡因组 ;LB组 :利多卡因 -布比卡因混合液组。选择肌间沟入路 ,应用神经刺激仪进行臂丛神经定位 ,定位准确后注射局麻药 ,RP组给 0 375 %罗哌卡因 2 0～ 2 5ml,LB组给 1%利多卡因 - 0 2 5 %布比卡因混合液 2 0～ 2 5ml。监测SBP、DBP、HR、SPO2 、EKG记录麻醉前、麻醉后 10min、30min、6 0min、术毕的SBP、DBP、HR、SPO2 ,采用 10cmVAS对镇痛效果进行评估 ,记录麻醉前、麻醉后 10min、30min、6 0min、术毕的VAS。结果　两组病人麻醉前、麻醉后 10min、30min、6 0min、术毕的SBP、DBP、HR、SPO2 ,差异无显著性 (P >0 0 5 )。RP组和LB组间比较差异无显著性 (P >0 0 5 )。EKG未见异常改变 ;两组病人麻醉阻滞效果比较 ,在麻醉后 10min两者之间存在显著差异 (P <0 0 5 ) ;其它时间点差异无显著性 (P >0 0 5 )。结论　罗哌卡因 (0 375 %,2 0～ 2 5ml)在臂丛麻醉中对血流动力学及SPO2 无显著影响 ,同时有肯定的麻醉阻滞效果。AIM To study anesthetic effect of ropivacaine in brachial plexus block. METHODS Forty patients were selected for the experiment, and were randomly divided into two groups. RP group (n=20) received 0.375% ropivacaine 20～25 ml while LB group (n=20) received 1.0% lidocanie plus 0.25% bupivacaine 20～25 ml. By interscalene route the nerve stimulator was used to locate brachial plexus. SBP,DBP,HR?SPO 2,EKG were monitored during anesthesia, and the SBP,DBP,HR,SPO 2 were recorded before anesthesia, at 10 min, 30 min and 60 min after anesthesia, at operative end. To evaluate the analgetic effect VAS was applied during anesthesia. The VAS values were recorded before anesthesia, at 10 min,30 min and 60 min after anesthesia, at operative end. RESULTS SBP,DBP,HR,SPO 2 were not significantly different between two groups and intra-group before anesthesia, at 10 min,30 min and 60 min after anesthesia, at operative end (P>0.05). The analgetic effect was significantly different at 10 min after anesthesia (P<0.05)but the VAS values were not significantly different at the other time(P>0.05)between two groups. CONCLUSION There was not significant effect of ropivacaine(0.375%, 20～25 ml) on hemodynamics & SPO 2 and was definite anesthetic action in the brachial plexus block simultaneously.

关 键 词：罗哌卡因 臂丛麻醉 比较研究 血液动力学 布比卡因 

分 类 号：R614.41[医药卫生—麻醉学]