降纤酶对脑梗死患者血浆纤维蛋白原含量及临床疗效的影响  

Defibrase effects on fibrinogen in patients with cerebrovascular disease and its clinical effecft

作　　者：潘剑罡[1] 韩陈保[1] 郑华[1] 

机构地区：[1]广东医学院附属医院,广东湛江524001

出　　处：《中国组织工程研究》2000年第13期6-7,共2页Chinese Journal of Tissue Engineering Research

基　　金：广东省医药卫生青年基金(B1998128)

摘　　要：目的探讨降纤酶对脑梗死患者血浆纤维蛋白原（Ｆｉｂ）含量的影响及临床疗效意义。方法比较８０例脑梗死患者和４０例对照组血浆Ｆｉｂ含量及降纤酶治疗的疗效。结果脑梗死患者血浆Ｆｉｂ含量较对照组显著升高（Ｐ＜０．０１），降纤酶治疗后Ｆｉｂ明显下降（Ｐ＜０．０１）。结论血浆Ｆｉｂ含量增高是脑梗死的独立危险因素；降纤酶能降低Ｆｉｂ水平，改善神经功能缺损程度。Objective To investigate defibrase effects fibrinogen(Fib) in patients with cerebrovascular disease(CVD). Method To compare Fib level in plasm in 80 patients with CVD with that in 40 normal donors, and compare therapy effect of defibrase. Result The Fib level in patients with CVD was higer than that in normal donors(P < 0. 01 ), Fib level decreased after defibrase therapy (P < 0. 01 ) Conclusion Increased Fib level was one of the risk factors of CVD, defibrase therapy would decrease the Fib level and improve the impaired neurological function.

关 键 词：降纤酶 纤维蛋白原 脑梗死 

分 类 号：R4[医药卫生—临床医学]