5-单硝异山梨醇酯和银杏叶并用治疗心绞痛疗效观察  

Clinical observation of 5-mono nitre isosorbide combined with ginkgo leaf in treating angina pectoris

作　　者：黄雄伟[1] 张书富[1] 查艳萍[2] 

机构地区：[1]上海市杨浦区中心医院,上海200090 [2]第二军医大学附属长海医院,上海200433

出　　处：《中成药》2002年第9期686-688,共3页Chinese Traditional Patent Medicine

摘　　要：目的 :比较 5 单硝异山梨醇酯和银杏叶并用与单用 5 单硝异山梨醇酯对心绞痛患者的疗效。方法 :10 0例心绞痛患者随机分为对照组 (5 单硝异山梨醇酯组 )和治疗组 (5 单硝异山梨醇酯和银杏叶并用组 )。疗程 4个月。结果 :5 单硝异山梨醇酯合用银杏叶组可明显减少硝酸甘油的消耗量。治疗组总有效率 95 .6 % ,高于单用 5 单硝异山梨醇酯 (85 .1% )(P <0 .0 5 )。结论 :银杏叶可明显增强 5 单硝异山梨醇酯对冠心病心绞痛疗效 。Objective: To observe clinical therapeutic effective of 5 mono nitre isosorbide combined with ginkgo leaf in the treatment of angina pectoris. Methods:100 cases of angina pectoris were randomly divided into control group (5 mono nitre isosorbide) and treated group (5 mononitre isosorbide combined with ginkgo leaf). The therapeutic course lasted four monthes. Results: Nitroglycerin consumption in treated group was lower significantly than that in control group. The effective rate was 94.8% in the treated group and 84.2% in the control group after four monthes ( P <0.05).Conclusion: 5 mono nitre isosorbide combined with ginkgo leaf can control angina effectively and attenuate the development of nitroglycerin tolerance in patients with angina.

关 键 词：治疗 疗效 5-单硝异山梨醇酯 银杏叶 心绞痛 耐药性 药物合用 

分 类 号：R541.4[医药卫生—心血管疾病]