米槁心乐滴丸对猫实验性心肌缺血的保护作用  

Protective effects of Migaoxinle Drop Pills on cats with experimental mycocardial ischemia

作　　者：齐敏友[1] 隋艳华[1] 邱德文[1] 

机构地区：[1]贵阳中医学院药理教研室,贵州贵阳550002

出　　处：《中成药》2002年第9期690-692,共3页Chinese Traditional Patent Medicine

基　　金：国家中医药管理局资助项目 (96L0 2 8) .

摘　　要：目的 :观察米槁心乐滴丸对实验性心肌缺血的保护作用。方法 :用结扎猫冠状动脉形成实验性急性心肌缺血模型 ,观察十二指肠给药后心外膜电极标测的心肌缺血程度及心肌缺血范围 ,硝基四氮唑篮染色显示梗塞区面积影响。结果 :米槁心乐滴丸具有明显减轻心肌缺血程度及缺血范围 ,减少梗塞区面积。结论 :米槁心乐滴丸对实验性心肌缺血有保护作用。Objective: To investigate the effects of Migaoxinle Drop Pills (Migao Cinnamon anel Bulbus Allii Macrostemi) (MDP) on cats with experimental myocardial ischemid.Methods: The coronary arteries was ligated to establish myocardial ischemic model and MDP was given through duodenum to observe its effects on myocardial ischemic limit and myocardial infarct area by N BT staining.Results: MDP could reduce the myocardial ischemic limit and myocardial infarct area.Conclusion: MDP could protect myocardia from ischemic damage.

关 键 词：米槁心乐滴丸 心肌缺血 药理作用 动物模型 

分 类 号：R285.5[医药卫生—中药学]