肠粘膜上皮细胞在天然免疫中的作用  

The role of intestinal epithelial cells in innate immune

作　　者：王岚[1] 高杰英[1] 等 

机构地区：[1]军事医学科学院微生物流行病研究所，北京100071

出　　处：《生物技术通讯》2002年第5期368-370,共3页Letters in Biotechnology

摘　　要：粘膜免疫是机体防御系统的主要成分。致病性细菌侵入机体后,首先遭遇到天然免疫的抵抗,随后产生获得性免疫,两者共同执行机体的防御功能,消灭入侵细菌。最近的研究表明上皮细胞对细菌感染有重要的免疫调节作用,在天然免疫与获得性免疫防御机制中起重要作用。本文重点介绍肠上皮细胞在天然免疫中的作用。Mucosal immunity is the major element of the defense system.The bacterial pathogens confront innate im-munity firstly when they invade host followed by acquired immunity.Both of them play defensive funtion to eliminish the invasive bacteria.Recent research suggest that epithelial cells posess important immune regulation on bacterial infection and play the vital role on innate immune response and acquired immune response.This review will eluci-date the mechanism of epithelial cells in innate immune.

关 键 词：肠粘膜上皮细胞 天然免疫 作用 粘膜免疫 

分 类 号：R392.1[医药卫生—免疫学]