沙丁胺醇加异丙托溴铵治疗喘息性支气管炎  

Treatment of Infantile Asthmatoid Bronchitis with Aerosol Inhalation of Salbutamol and Ipratropium Bromide

作　　者：施月菊[1] 陈宝川[1] 苏梅玉[1] 陈萍萍[1] 卓志强[1] 

机构地区：[1]福建省泉州市儿童医院,362000

出　　处：《医药导报》2002年第10期651-652,共2页Herald of Medicine

摘　　要：目的 :观察空气压缩泵雾化吸入沙丁胺醇加异丙托溴铵治疗婴幼儿喘息性支气管炎的效果。方法 :喘息性支气管炎患儿 74例 ,分为治疗组 3 5例 ,以空气压缩泵雾化吸入 0 .5 %沙丁胺醇 0 .2 5mL·次 1和 0 .0 2 5 %异丙托溴铵 0 .5mL·次 1加 0 .9%氯化钠溶液至 2～ 3mL ,空气压缩泵雾化吸入 ,bid ,每次 10～ 15min ,疗程 3～ 7d ;对照组 3 9例 ,不加雾化。两组患儿其他治疗均相同。结果 :治疗组有效率 94.3 % ,对照组有效率 64 .1% (P <0 .0 1)。结论 :沙丁胺醇加异丙托溴铵雾化吸入治疗婴幼儿喘息性支气管炎能减轻症状 ,缩短病程 ,改善预后。Objective:To survey the clinical effect of aerosol inhalation of sulbutamol and ipratropium bromide in the treatment of infantile asthmatoid bronchitis with a nebulization device. Method:74 cases of infantile aothmoid bronchitis were divided into the treatment group (35 cases) and control group (39 cases). Patients of the treatment group were given each an aerosol inhalation of 0.25 mL of 0.5% salbutamol and 0.5 mL of 0.025% ipratropium bromide in 2～3 mL of 0.9% sodium chloride solution with the use of a nebalization device including an air pump. Inhalation was given bid. Patients of the control group were not given aerosol inhalation. Other treatment in both groups was identical. Results:The total effective rate in patients of the treatment group was 94.3% while that in patients of the control group was 64.1%( P <0.01). Conclusion:Treatment of infantile asthmatoid bronchitis with aerosol inhalation of salbutamol and ipratropium bromide was found to relieve symptoms shorten the course of the disease, and improve the prognosis.

关 键 词：沙丁胺醇 异丙托溴铵 支气管炎 喘息性 婴幼儿 雾化吸入 治疗 

分 类 号：R562.210.5[医药卫生—呼吸系统]