激光诱导间质热疗中的治疗参数选择  

Therapeutic parameter selection during the Laser-induced Interstitial Thermotherapy

作　　者：马宁[1] 江世臣[1] 李和杰[1] 张学学[1] 

机构地区：[1]清华大学热能工程系工程热物理研究所,北京100084

出　　处：《激光杂志》2002年第5期59-61,共3页Laser Journal

摘　　要：目的:考察激光诱导间质热疗中各治疗参数对治疗效果的影响,对各治疗参数进行选择和优化。方法:基于光子传输理论,分别采用Monte　Carlo模拟方法和Pennes生物传热方程求解生物组织中的能量分布和温度分布。结果:计算得到了一般加热系统、具有冷却设备的加热系统以及暂时阻断血液灌注条件下,激光波长、功率大小及激光加入头曝光时间对凝结区域大小的影响。结论:激光诱导间质热疗中,需要综合考虑生物组织特性和激光波长、功率及曝光时间等治疗参数来制定治疗方案。Objective:To investigate the influence of different therapeutic parameters on the therapeutic effect, and then to choose and optimize these parameters. Method;Based on the photon transport theory, to solve the energy and temperature distributions using Monte Carlo simulation and Pennes Bio-heat transfer equation,respectively. ResultsiHaving got influences of the laser wavelength, power density and the exposure duration of laser probe on the coagulation size for the ordinary LITTsystem and LITT systems with cooling equipment and blood obstruction,respectively.ConclusiontDuring a LITT treatment, the Rx should be based on the general consideration of different biological properties and the laser wavelength,laser power and the laser probe exposure duration.

关 键 词：激光 诱导 间质热疗 治疗参数 激光生物作用 肿瘤热疗 生物传热 

分 类 号：R454.5[医药卫生—治疗学]