氯硝柳胺三种配伍剂浸杀钉螺作用的研究  

Research of the killing effect of three compound with nidosamide on Oncomemalauia snail.

作　　者：朱丹[1,2] 谢法仙[1,2] 鲍子平[1,2] 朱达培 倪传华 

机构地区：[1]中国疾病控制中心寄生虫病预防控制所,上海市200025 [2]卫生部寄生虫病与媒介生物学重点实验室

出　　处：《中国热带医学》2002年第3期307-308,共2页China Tropical Medicine

基　　金："九.五"国家科技攻关资助课题(No.96-906-04-05)

摘　　要：目的 比较氯硝柳胺(niclosamide)与杀虫丁[(dimethylamine)trithacyclohexane hydrochloride]、83051(N-pyrib-ine-3-N’-phenyl ureahydrochlorate)、茶树籽[Seed of Camellia sinensis(L)O.Kuntze]配伍的杀螺效果。方法 采用实验室浸杀方法观察氯硝柳胺三种配伍剂的杀螺效果。结果 氯硝柳胺0.2mg/L分别与杀虫丁0.1mg/L、83051 4m/L和茶树籽10mg/L配伍,其浸杀钉螺LC90分别为0.198mg/L,0.175mg/L和0.151mg/L。结论 氯硝柳胺与杀虫丁配伍剂浸杀钉螺效果较好,氯硝柳胺与83051配伍剂适宜水产经济区使用,氯硝柳胺与茶树籽配伍剂能降低灭螺成本。Objective hi order to develop a molluscicide which has a good killing effect on snail, especially, on inhibition of climbing of Oncomelania snail. Methods Experiments of immersed- molluscicide and spray- molluscicide in room to kill snail and inhibition of snail- climbing were conducted in the laboratory to observe the mortality of snail and inhibition of snail crawling with the three Compounds and niclosamide ,respectively, and niclosamide as control group, their compounds were screened. Result The dose of LC90 molluscicide is 0.198 mg/L,0. 175mg/L and 0. 151mg/L when 0.2mg/L niclosamide combined with 0. 1 mg/L 'Shachongding',4mg/L 83051 and lOmg/L SCS, respectively, which have effects of molluscicide as well as niclosamide's and inhibits 90% snail to climb. Conclusion The screened niclosamide compound regime that is niclosamide with 'Shachongding' can inhibit snail climbing effectively. The compound of 83051 with niclosamide is suitable to be utilized in areas with aquatic products. SCS with niclosamide could reduce the cost of molluscicide.

关 键 词：氯硝柳胺 杀虫丁 茶树籽 配伍剂 杀螺剂 血吸虫病 

分 类 号：R532.21[医药卫生—内科学] R978.8[医药卫生—临床医学]