生物组织折射率测量的一种简便方法  

A Simple Method for Refractive Index Measurement of Bio-tissue

作　　者：王新宇[1] 张春平[1] 张连顺[1] 薛玲玲[1] 田建国[1] 

机构地区：[1]南开大学物理学院光子学中心,天津300071

出　　处：《光电子．激光》2002年第9期976-978,共3页Journal of Optoelectronics·Laser

摘　　要：提出了一种基于光学相干层析 (OCT)测量生物组织折射率的光程匹配法。该方法通过缩短测量时间 ,保证了测得的折射率接近于生理状态。测量了标准样品熔石英及真实样品黄瓜浅表层在 85 0 nm和130 0 nm波长下的折射率 ,验证了方法的有效性和可靠性。分析表明 ,光程匹配法是对焦点追迹法的有效补充。Optical path matching method is presented for simultaneous measurement of refractive index and thickness of bio tissue.This method is based on optical coherence tomography(OCT) and shortens the measure time largely.It spends only two minutes to get all the parameters needed.The shortening of time will ensure that the measured values are close to physiological status.Through the measurements of the refractive indices of a fused silica with the thickness of 1 [KG-1/6]036 μm and the sub surface of a cucumber at the wavelengths of 850 nm and 1 [KG-1/6]300 nm,the validity of this method is proved.It provides a good supplement for focus tracking method.

关 键 词：光程匹配法 光学相干层析 OCT 生物组织 折射率 厚度 

分 类 号：R318.51[医药卫生—生物医学工程] TN247[医药卫生—基础医学]